Significance of lymphocytic sister chromatid exchange frequencies in ovarian cancer patients

Pawan Kumar Dhar, Sulochna Devi, T. Ramesh Rao, Usha Kumari, Anita Joseph, M. R. Kumar, Satish Nayak, Y. Shreemati, S. M. Bhat, K. R. Bhat

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Very few studies report the analysis of sister chromatid exchanges in ovarian cancer patients. We tested the null hypothesis that SCE frequency increases with the advancing stages of ovarian cancer and follows a Poisson distribution. As controls we examined age- and sex-matched healthy volunteers who had no such past history. An increased average SCE frequency was observed in ovarian cancer patients (6.34 ± 0.09) vis-a-vis controls (4.47 ± 0.12). Further, the data also suggested a stage-wise increase in the SCE frequency.

Original languageEnglish
Pages (from-to)105-108
Number of pages4
JournalCancer Genetics and Cytogenetics
Volume89
Issue number2
DOIs
Publication statusPublished - 15-07-1996
Externally publishedYes

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Sister Chromatid Exchange
Ovarian Neoplasms
Poisson Distribution
Healthy Volunteers

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Genetics
  • Cancer Research

Cite this

Kumar Dhar, P., Devi, S., Ramesh Rao, T., Kumari, U., Joseph, A., Kumar, M. R., ... Bhat, K. R. (1996). Significance of lymphocytic sister chromatid exchange frequencies in ovarian cancer patients. Cancer Genetics and Cytogenetics, 89(2), 105-108. https://doi.org/10.1016/0165-4608(95)00071-2
Kumar Dhar, Pawan ; Devi, Sulochna ; Ramesh Rao, T. ; Kumari, Usha ; Joseph, Anita ; Kumar, M. R. ; Nayak, Satish ; Shreemati, Y. ; Bhat, S. M. ; Bhat, K. R. / Significance of lymphocytic sister chromatid exchange frequencies in ovarian cancer patients. In: Cancer Genetics and Cytogenetics. 1996 ; Vol. 89, No. 2. pp. 105-108.
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Kumar Dhar, P, Devi, S, Ramesh Rao, T, Kumari, U, Joseph, A, Kumar, MR, Nayak, S, Shreemati, Y, Bhat, SM & Bhat, KR 1996, 'Significance of lymphocytic sister chromatid exchange frequencies in ovarian cancer patients', Cancer Genetics and Cytogenetics, vol. 89, no. 2, pp. 105-108. https://doi.org/10.1016/0165-4608(95)00071-2

Significance of lymphocytic sister chromatid exchange frequencies in ovarian cancer patients. / Kumar Dhar, Pawan; Devi, Sulochna; Ramesh Rao, T.; Kumari, Usha; Joseph, Anita; Kumar, M. R.; Nayak, Satish; Shreemati, Y.; Bhat, S. M.; Bhat, K. R.

In: Cancer Genetics and Cytogenetics, Vol. 89, No. 2, 15.07.1996, p. 105-108.

Research output: Contribution to journalArticle

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