Significance of MRSA strains in community associated skin and soft tissue infections

M. S. Shenoy, G. K. Bhat, A. Kishore, M. K. Hassan

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

The study was conducted to determine the antibiotic susceptibility profile of community-associated methicillin resistant Staphylococcus aureus (CAMRSA) strains isolated from infections. S. aureus strains were isolated from clinical specimens using the standard procedures. CDC definition was used to classify CAMRSA. Antibiotic susceptibility test was done using Kirby-Bauer disk diffusion method. Double disk diffusion method (D-test) was used to detect inducible macrolide, lincosamide and streptograminB resistance (inducible MLSB resistance). A total of 83 CAMRSA were isolated from abscesses and other skin infections in persons without known risk factors for MRSA infection. All CAMRSA were susceptible to vancomycin. Out of 83 CAMRSA, 13 (15.65%) were D-test positive (inducible MLSB positive) and 6 (7.23%) were positive for constitutive MLSB resistance. Eight strains (9.63%) were resistant to tetracycline and 26 (31.32%) strains were resistant to erythromycin. Increased rate of inducible clindamycin resistance among CAMRSA indicates the importance of identification of such strains by D test to avoid treatment failure when clindamycin is used.

Original languageEnglish
Pages (from-to)152-154
Number of pages3
JournalIndian Journal of Medical Microbiology
Volume28
Issue number2
DOIs
Publication statusPublished - 01-04-2010

Fingerprint

Soft Tissue Infections
Methicillin-Resistant Staphylococcus aureus
Skin
Clindamycin
Disk Diffusion Antimicrobial Tests
Infection
Lincosamides
Anti-Bacterial Agents
Macrolides
Erythromycin
Vancomycin
Centers for Disease Control and Prevention (U.S.)
Tetracycline
Treatment Failure
Abscess
Staphylococcus aureus

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)

Cite this

@article{55856c7c966341c58fd0235591a36ae6,
title = "Significance of MRSA strains in community associated skin and soft tissue infections",
abstract = "The study was conducted to determine the antibiotic susceptibility profile of community-associated methicillin resistant Staphylococcus aureus (CAMRSA) strains isolated from infections. S. aureus strains were isolated from clinical specimens using the standard procedures. CDC definition was used to classify CAMRSA. Antibiotic susceptibility test was done using Kirby-Bauer disk diffusion method. Double disk diffusion method (D-test) was used to detect inducible macrolide, lincosamide and streptograminB resistance (inducible MLSB resistance). A total of 83 CAMRSA were isolated from abscesses and other skin infections in persons without known risk factors for MRSA infection. All CAMRSA were susceptible to vancomycin. Out of 83 CAMRSA, 13 (15.65{\%}) were D-test positive (inducible MLSB positive) and 6 (7.23{\%}) were positive for constitutive MLSB resistance. Eight strains (9.63{\%}) were resistant to tetracycline and 26 (31.32{\%}) strains were resistant to erythromycin. Increased rate of inducible clindamycin resistance among CAMRSA indicates the importance of identification of such strains by D test to avoid treatment failure when clindamycin is used.",
author = "Shenoy, {M. S.} and Bhat, {G. K.} and A. Kishore and Hassan, {M. K.}",
year = "2010",
month = "4",
day = "1",
doi = "10.4103/0255-0857.62494",
language = "English",
volume = "28",
pages = "152--154",
journal = "Indian Journal of Medical Microbiology",
issn = "0255-0857",
publisher = "Medknow Publications and Media Pvt. Ltd",
number = "2",

}

Significance of MRSA strains in community associated skin and soft tissue infections. / Shenoy, M. S.; Bhat, G. K.; Kishore, A.; Hassan, M. K.

In: Indian Journal of Medical Microbiology, Vol. 28, No. 2, 01.04.2010, p. 152-154.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Significance of MRSA strains in community associated skin and soft tissue infections

AU - Shenoy, M. S.

AU - Bhat, G. K.

AU - Kishore, A.

AU - Hassan, M. K.

PY - 2010/4/1

Y1 - 2010/4/1

N2 - The study was conducted to determine the antibiotic susceptibility profile of community-associated methicillin resistant Staphylococcus aureus (CAMRSA) strains isolated from infections. S. aureus strains were isolated from clinical specimens using the standard procedures. CDC definition was used to classify CAMRSA. Antibiotic susceptibility test was done using Kirby-Bauer disk diffusion method. Double disk diffusion method (D-test) was used to detect inducible macrolide, lincosamide and streptograminB resistance (inducible MLSB resistance). A total of 83 CAMRSA were isolated from abscesses and other skin infections in persons without known risk factors for MRSA infection. All CAMRSA were susceptible to vancomycin. Out of 83 CAMRSA, 13 (15.65%) were D-test positive (inducible MLSB positive) and 6 (7.23%) were positive for constitutive MLSB resistance. Eight strains (9.63%) were resistant to tetracycline and 26 (31.32%) strains were resistant to erythromycin. Increased rate of inducible clindamycin resistance among CAMRSA indicates the importance of identification of such strains by D test to avoid treatment failure when clindamycin is used.

AB - The study was conducted to determine the antibiotic susceptibility profile of community-associated methicillin resistant Staphylococcus aureus (CAMRSA) strains isolated from infections. S. aureus strains were isolated from clinical specimens using the standard procedures. CDC definition was used to classify CAMRSA. Antibiotic susceptibility test was done using Kirby-Bauer disk diffusion method. Double disk diffusion method (D-test) was used to detect inducible macrolide, lincosamide and streptograminB resistance (inducible MLSB resistance). A total of 83 CAMRSA were isolated from abscesses and other skin infections in persons without known risk factors for MRSA infection. All CAMRSA were susceptible to vancomycin. Out of 83 CAMRSA, 13 (15.65%) were D-test positive (inducible MLSB positive) and 6 (7.23%) were positive for constitutive MLSB resistance. Eight strains (9.63%) were resistant to tetracycline and 26 (31.32%) strains were resistant to erythromycin. Increased rate of inducible clindamycin resistance among CAMRSA indicates the importance of identification of such strains by D test to avoid treatment failure when clindamycin is used.

UR - http://www.scopus.com/inward/record.url?scp=77951751947&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77951751947&partnerID=8YFLogxK

U2 - 10.4103/0255-0857.62494

DO - 10.4103/0255-0857.62494

M3 - Article

VL - 28

SP - 152

EP - 154

JO - Indian Journal of Medical Microbiology

JF - Indian Journal of Medical Microbiology

SN - 0255-0857

IS - 2

ER -