Abstract

Maintaining glucose concentration in normoglycemic range in Type I diabetic patients is challenging. In this study H control is applied for insulin delivery to prevent hyperglycemic levels in a type I diabetic patient. From a control theory point of view, the blood glucose regulation problem is reformulated as a tracking one. A glucose tolerance curve (GTC) validated from several patients is used as a reference model. Intra-and inter-patient variability poses a challenging task to control blood glucose concentration in diabetic patients. A data based robust controller is developed to control blood glucose concentration in type I diabetic patients in the presence of meal disturbances under patient-model mismatch. Simulation studies are performed on the diabetic patient model under feedback control which revealed that the proposed control strategy is able to control blood glucose concentration well within the acceptable limits and also compensate for slow parametric drifts.

Original languageEnglish
Pages (from-to)287-293
Number of pages7
JournalIETE Journal of Research
Volume55
Issue number6
DOIs
Publication statusPublished - 01-11-2009

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Glucose
Simulation Study
Blood
Insulin
Reference Model
Control theory
Control Theory
Feedback Control
Feedback control
Tolerance
Control Strategy
Disturbance
Controller
Controllers
Curve
Model
Range of data

All Science Journal Classification (ASJC) codes

  • Theoretical Computer Science
  • Computer Science Applications
  • Electrical and Electronic Engineering

Cite this

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title = "Simulation study on type i diabetic patient",
abstract = "Maintaining glucose concentration in normoglycemic range in Type I diabetic patients is challenging. In this study H∞ control is applied for insulin delivery to prevent hyperglycemic levels in a type I diabetic patient. From a control theory point of view, the blood glucose regulation problem is reformulated as a tracking one. A glucose tolerance curve (GTC) validated from several patients is used as a reference model. Intra-and inter-patient variability poses a challenging task to control blood glucose concentration in diabetic patients. A data based robust controller is developed to control blood glucose concentration in type I diabetic patients in the presence of meal disturbances under patient-model mismatch. Simulation studies are performed on the diabetic patient model under feedback control which revealed that the proposed control strategy is able to control blood glucose concentration well within the acceptable limits and also compensate for slow parametric drifts.",
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Simulation study on type i diabetic patient. / Kamath, Surekha; Vidyasagar, Sudha; V I, George.

In: IETE Journal of Research, Vol. 55, No. 6, 01.11.2009, p. 287-293.

Research output: Contribution to journalArticle

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