Salbutamol sulphate is a bronchodilator and ambroxol hydrochloride is an expectorant. Simple, precise rapid and selective simultaneous equation and Q-analysis UV spectrophotometric methods have been developed for the simultaneous determination of salbutamol and ambroxol from combined tablet dosage forms. The methods involves solving of simultaneous equation and Q-value analysis based on measurement of absorptivity at 232,244 and 276 nm. Linearity lies between 10-50 mcg/mL for ambroxol and 1-15 mcg/mL for salbutamol.
|Number of pages||4|
|Publication status||Published - 2005|
Srinivasan, K. K., Shirwaikar, A., Joseph, A., Jacob, S., & Prabu, L. S. (2005). Simultaneous estimation for the analysis of salbutamol sulphate and ambroxol hydrochloride in solid dosage forms by ultraviolet spectrophotometry. Indian Drugs, 42(9), 576-579.