Simultaneous UV spectrophotometric estimation of ambroxol hydrochloride and levocetirizine dihydrochloride

S. Prabu, A. Shirwaikar, C. Kumar, G. Kumar

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

A novel, simple, sensitive and rapid spectrophotometric method has been developed for simultaneous estimation of ambroxol hydrochloride and levocetirizine dihydrochloride. The method involved solving simultaneous equations based on measurement of absorbance at two wavelengths 242 nm and 231 nm, the g max of ambroxol hydrochloride and levocetirizine dihydrochloride, respectively. Beer's law was obeyed in the concentration range 10-50 μg/ml and 8-24 μg/ml for ambroxol hydrochloride and levocetirizine dihydrochloride respectively. Results of the method were validated statistically and by recovery studies.
Original languageEnglish
Pages (from-to)236-238
Number of pages3
JournalIndian Journal of Pharmaceutical Sciences
Volume70
Issue number2
DOIs
Publication statusPublished - 2008

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