Size dependent studies of metal nanoparticles with bio-fluorophores

Ajeetkumar Patil; Steffy Ballary; Sajan D. George; Santhosh Chidangil

doi:10.1117/12.2271289

Size dependent studies of metal nanoparticles with bio-fluorophores

Ajeetkumar Patil, Steffy Ballary, Sajan D. George, Santhosh Chidangil

Department of Atomic and Molecular Physics, Manipal

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Citation (Scopus)

Abstract

Interaction of noble metal nanoparticles (NPs) with fluorophores has been an important research area in the field of material science and biomedical field. In the proximity of a metal nanoparticle, there is a quenching or enhancement in the intrinsic fluorescence of the fluorophore. The conditional quenching of the fluorescence can be used for negative sensing whereas enhancement in the fluorescence can be used to gain greater sensitivity and high signal to noise ratio in the molecular sensing/imaging. The current work deals with the systematic studies to understand the fluorescence quenching for few bio-fluorophores (NADH and FAD) when interacted with different sized silver nano-particles of (10nm, 40nm and 100nm). Home assembled Laser Induced Fluorescence (LIF) set-up was used to study the fluorescence quenching of NADH and FAD for different sized silver nanoparticles.

Original language	English
Title of host publication	Fifth International Conference on Optical and Photonics Engineering
Publisher	SPIE
Volume	10449
ISBN (Electronic)	9781510613720
DOIs	https://doi.org/10.1117/12.2271289
Publication status	Published - 01-01-2017
Event	5th International Conference on Optical and Photonics Engineering - Singapore, Singapore Duration: 04-04-2017 → 07-04-2017

Conference

Conference	5th International Conference on Optical and Photonics Engineering
Country	Singapore
City	Singapore
Period	04-04-17 → 07-04-17

All Science Journal Classification (ASJC) codes

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

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10.1117/12.2271289

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Patil, A., Ballary, S., George, S. D., & Chidangil, S. (2017). Size dependent studies of metal nanoparticles with bio-fluorophores. In Fifth International Conference on Optical and Photonics Engineering (Vol. 10449). [104493B] SPIE. https://doi.org/10.1117/12.2271289

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abstract = "Interaction of noble metal nanoparticles (NPs) with fluorophores has been an important research area in the field of material science and biomedical field. In the proximity of a metal nanoparticle, there is a quenching or enhancement in the intrinsic fluorescence of the fluorophore. The conditional quenching of the fluorescence can be used for negative sensing whereas enhancement in the fluorescence can be used to gain greater sensitivity and high signal to noise ratio in the molecular sensing/imaging. The current work deals with the systematic studies to understand the fluorescence quenching for few bio-fluorophores (NADH and FAD) when interacted with different sized silver nano-particles of (10nm, 40nm and 100nm). Home assembled Laser Induced Fluorescence (LIF) set-up was used to study the fluorescence quenching of NADH and FAD for different sized silver nanoparticles.",

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