Sodium alginate and gelatin hydrogels: Viscosity effect on hydrophobic drug release

Utkarsh Bhutani, Anindita Laha, Kishalay Mitra, Saptarshi Majumdar

Research output: Contribution to journalArticlepeer-review

51 Citations (Scopus)

Abstract

Blend of biodegradable hydrogels like sodium alginate/gelatin (SA/G) usually requires use of chemical cross-linkers to remain stable in aqueous media for drug delivery applications. This study targets the feasibility of having an entire spectrum of a model hydrophobic drug (piperine) release i.e. from burst to controlled release, by varying polymer viscosity and molecular weight of plasticizer with minimal use of cross-linkers. Swelling study, drug-polymer interactions and morphology analysis reveal the impact of viscosity variation on polymer matrix.

Original languageEnglish
Pages (from-to)76-79
Number of pages4
JournalMaterials Letters
Volume164
DOIs
Publication statusPublished - 01-02-2016

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

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