Sodium hypochlorite reduces postoperative discomfort and painful early failure after carious exposure and direct pulp capping—initial findings of a randomized controlled trial

Nidambur Vasudev Ballal, Henry F. Duncan, Namith Rai, Prateek Jalan, Matthias Zehnder

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

In this randomized controlled single-center clinical trial on 96 adult patients with parallel experimental groups (n = 48), the effects of washing a dentin/pulp wound in non-symptomatic teeth with extremely deep caries and pulpal exposure were compared between a 2.5% sodium hypochlorite (NaOCl) solution and a chemically-inert physiological saline control solution. After the allocated wound lavage, the pulps were capped with a mineral trioxide aggregate, covered by a glass-ionomer/resin liner, and the teeth were immediately restored with a resin-bonded-composite. In this first report, the early events were analyzed: postoperative discomfort (on an NRS-11 scale) at day-3 and-7 after intervention, and the occurrence of unbearable pain causing patients to contact the principal investigator to perform a root canal treatment (pulpectomy) during the first three months. The NaOCl solution caused a highly significant reduction in post-operative discomfort (p = 0.0010 day 3; p = 0.0007 day 7) and early painful failures (p = 0.0008) compared with the control. These novel findings highlight the importance of infection control in teeth with extremely deep carious lesions. Based on these observations, the use of an NaOCl solution to wash the exposed dentin/pulp wound in the vital pulp treatment is highly recommended in order to reduce pain and early failure.

Original languageEnglish
Article number2408
Pages (from-to)1-11
Number of pages11
JournalJournal of Clinical Medicine
Volume9
Issue number8
DOIs
Publication statusPublished - 01-08-2020

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Fingerprint

Dive into the research topics of 'Sodium hypochlorite reduces postoperative discomfort and painful early failure after carious exposure and direct pulp capping—initial findings of a randomized controlled trial'. Together they form a unique fingerprint.

Cite this