Solubility behaviour of 3-phenylsyndone in binary solvents

C.V.S. Subrahmanyam, K. Krishna Mohan, K. Satyanaryana

Research output: Contribution to journalArticle

Abstract

The solubility of a type A meso-ionic compound, 3-phenylsydnone was determined in dioxane-water and ethylacetate-methanol, methanol-water solvent series. The experimental mole fraction solubility was well below the ideal solubility, indicating strong self-association of solvent or solute or both. However, the solubility parameter values obtained by Fedors and Hoy group contribution methods, peak solubility and regression methods were found to be in good agreement. A value of 11.3 H is assigned to the solubility parameter of 3-phenylsydnone.
Original languageUndefined/Unknown
Pages (from-to)151-156
Number of pages6
JournalIndian Journal of Pharmaceutical Sciences
Volume57
Issue number4
Publication statusPublished - 1995

Cite this

Subrahmanyam, C. V. S., Krishna Mohan, K., & Satyanaryana, K. (1995). Solubility behaviour of 3-phenylsyndone in binary solvents. Indian Journal of Pharmaceutical Sciences, 57(4), 151-156.
Subrahmanyam, C.V.S. ; Krishna Mohan, K. ; Satyanaryana, K. / Solubility behaviour of 3-phenylsyndone in binary solvents. In: Indian Journal of Pharmaceutical Sciences. 1995 ; Vol. 57, No. 4. pp. 151-156.
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Subrahmanyam, CVS, Krishna Mohan, K & Satyanaryana, K 1995, 'Solubility behaviour of 3-phenylsyndone in binary solvents', Indian Journal of Pharmaceutical Sciences, vol. 57, no. 4, pp. 151-156.

Solubility behaviour of 3-phenylsyndone in binary solvents. / Subrahmanyam, C.V.S.; Krishna Mohan, K.; Satyanaryana, K.

In: Indian Journal of Pharmaceutical Sciences, Vol. 57, No. 4, 1995, p. 151-156.

Research output: Contribution to journalArticle

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T1 - Solubility behaviour of 3-phenylsyndone in binary solvents

AU - Subrahmanyam, C.V.S.

AU - Krishna Mohan, K.

AU - Satyanaryana, K.

N1 - cited By 0

PY - 1995

Y1 - 1995

N2 - The solubility of a type A meso-ionic compound, 3-phenylsydnone was determined in dioxane-water and ethylacetate-methanol, methanol-water solvent series. The experimental mole fraction solubility was well below the ideal solubility, indicating strong self-association of solvent or solute or both. However, the solubility parameter values obtained by Fedors and Hoy group contribution methods, peak solubility and regression methods were found to be in good agreement. A value of 11.3 H is assigned to the solubility parameter of 3-phenylsydnone.

AB - The solubility of a type A meso-ionic compound, 3-phenylsydnone was determined in dioxane-water and ethylacetate-methanol, methanol-water solvent series. The experimental mole fraction solubility was well below the ideal solubility, indicating strong self-association of solvent or solute or both. However, the solubility parameter values obtained by Fedors and Hoy group contribution methods, peak solubility and regression methods were found to be in good agreement. A value of 11.3 H is assigned to the solubility parameter of 3-phenylsydnone.

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VL - 57

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EP - 156

JO - Indian Journal of Pharmaceutical Sciences

JF - Indian Journal of Pharmaceutical Sciences

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Subrahmanyam CVS, Krishna Mohan K, Satyanaryana K. Solubility behaviour of 3-phenylsyndone in binary solvents. Indian Journal of Pharmaceutical Sciences. 1995;57(4):151-156.