Spatially controlled DNA unzipping by microfluidic interface positioning on a molecule perpendicular to a multicomponent flow

Naresh K. Mani, Sergii Rudiuk, Damien Baigl

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

A DNA molecule is rotated under a transversal electric field to be perpendicular to a longitudinal, multicomponent microfluidic flow. Positioning the interface allows us to control DNA unzipping with spatio-temporal resolution. This demonstrates that a microfluidic gradient can be applied at the single molecule level for a dynamic intramolecular stimulation.

Original languageEnglish
Pages (from-to)6858-6860
Number of pages3
JournalChemical Communications
Volume49
Issue number61
DOIs
Publication statusPublished - 07-08-2013

Fingerprint

Microfluidics
DNA
Molecules
Electric fields

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Cite this

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Spatially controlled DNA unzipping by microfluidic interface positioning on a molecule perpendicular to a multicomponent flow. / Mani, Naresh K.; Rudiuk, Sergii; Baigl, Damien.

In: Chemical Communications, Vol. 49, No. 61, 07.08.2013, p. 6858-6860.

Research output: Contribution to journalArticle

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