@article{9a9796f8a3f64123ade0bbc66090fd02,
title = "Spectrofluorimetric method for determination of citalopram in bulk and pharmaceutical dosage forms",
abstract = "A simple accurate, sensitive reproducible spectrofluorimetric method was developed for the analysis of citalopram in pure and pharmaceutical dosage form. Citalopram showed strong native fluorescence in 0.05 M sulphuric acid having excitation at 239 nm and emission at 300 nm. All parameters like the effect of different solvents, pH, dilutions, reaction time, temperature and effect of excipients were thoroughly investigated. The calibration graph was linear in the range from 0.100 to 0.900 mg/ml. The proposed method was statistically validated and successfully applied for analysis of tablet dosage forms. The percentage recovery was found to be between 99.08% to 99.28%.",
author = "S. Vasantharaju and S. Prabu and A. Jacob",
note = "Cited By :11 Export Date: 10 November 2017 CODEN: IJSID Correspondence Address: Vasantharaju, S.; Dept. of Pharmaceutical Quality Assurance, Manipal College of Pharmaceutical Sciences, Manipal-576 104, India; email: sgvasanth65@gmail.com Chemicals/CAS: citalopram, 59729-33-8; sulfuric acid, 7664-93-9 Manufacturers: Torrent, India References: Budavari S. editor. The Merck Index, 14th ed. Whitehouse Station, NJ: Merck and Co., Inc; 2007. p. 387; Baldessarini, R.J., (2006) The Pharmacological basis of therapeutics, pp. 449-450. , Beunton LL, Lazo JS, Parker KL, editors, 11th ed. New Delhi: Medical Publishing Division;; Kristoffersen, L., Bugge, A., Lundanes, E., Slordal, L., Simultaneous determination of citalopram, fluoxetine, paroxetine and their metabolites in plasma and whole blood by high-performance chromatography with ultraviolet and fluorescence detection (1999) J Chromatogr B Biomed Sci Appl, 734, pp. 229-246; Kosel, M., Eapey, M., Baumann, P., Analysis of the enantiomers of citalopram and its demethylated metabolites using chiral liquid chromatography (1998) J Chromatogr B Biomed Sci Appl, 719, pp. 234-238; Matsui, E., Hoshino, M., Matsui, A., Okahira, A., Simultaneous determination of citalopram and its metabolites by high-performance liquid chromatography with column switching and fluoresence detection by direct plasma injection (1995) J Chromatogr B Biomed Sci Appl, 668, pp. 299-307; Oyehaug, E., Ostensen, E.T., Salvesen, B., High-performance liquid chromatographic determination of citalopram and four of its metabolites in plasma and urine samples from psychiatric patients (1984) J Chromatogr, 308, pp. 199-208",
year = "2008",
doi = "10.4103/0250-474X.45407",
language = "English",
volume = "70",
pages = "647--648",
journal = "Indian Journal of Pharmaceutical Sciences",
issn = "0250-474X",
publisher = "Medknow Publications and Media Pvt. Ltd",
number = "5",
}