Spectrophotometric determination of granisetron hydrochloride from bulk and its formulation

A. Shirwaikar, L.S. Prabu, D.C. Kumar, R. Kumar

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

A new simple, sensitive spectrophotometric method in ultraviolet region has been developed for the determination of granisetron hydrochloride in bulk drug and its pharmaceutical formulation. Granisetron hydrochloride exhibited maximum absorbance at 302 nm with apparent molar absorptivity 1.3258X 104 in methanol. It obeyed Beer's law in the concentration range of 6 - 20 mcg/mL Results of the analysis were validated statistically and by recovery studies.
Original languageEnglish
Pages (from-to)606-609
Number of pages4
JournalIndian Drugs
Volume44
Issue number8
Publication statusPublished - 2007
Externally publishedYes

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