A new simple, sensitive spectrophotometric method in ultraviolet region has been developed for the determination of granisetron hydrochloride in bulk drug and its pharmaceutical formulation. Granisetron hydrochloride exhibited maximum absorbance at 302 nm with apparent molar absorptivity 1.3258X 104 in methanol. It obeyed Beer's law in the concentration range of 6 - 20 mcg/mL Results of the analysis were validated statistically and by recovery studies.
|Number of pages||4|
|Publication status||Published - 2007|