Abstract

The present study focuses on the evaluation of the effect of He-Ne laser on tissue regeneration by monitoring collagen synthesis in wound granulation tissues in Swiss albino mice using analysis of laser induced fluorescence (LIF) and light microscopy techniques. The spectral analyses of the wound granulation tissues have indicated a dose dependent increase in collagen levels during the post-wounding days. The histological examinations on the other hand have also shown a significant increase in collagen deposition along with the reduced edema, leukocytes, increased granulation tissue, and fibroblast number in the optimal laser dose treated group compared to the non-illuminated controls.

Original languageEnglish
Pages (from-to)168-184
Number of pages17
JournalJournal of Biophotonics
Volume5
Issue number2
DOIs
Publication statusPublished - 02-2012

Fingerprint

wound healing
Granulation
Granulation Tissue
Collagen
progressions
Wound Healing
therapy
Lasers
collagens
Tissue
evaluation
lasers
Tissue regeneration
Fluorescence microscopy
Wounds and Injuries
Fibroblasts
Fluorescence Microscopy
edema
dosage
leukocytes

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Materials Science(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Engineering(all)
  • Physics and Astronomy(all)

Cite this

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title = "Spectroscopic and histological evaluation of wound healing progression following Low Level Laser Therapy (LLLT)",
abstract = "The present study focuses on the evaluation of the effect of He-Ne laser on tissue regeneration by monitoring collagen synthesis in wound granulation tissues in Swiss albino mice using analysis of laser induced fluorescence (LIF) and light microscopy techniques. The spectral analyses of the wound granulation tissues have indicated a dose dependent increase in collagen levels during the post-wounding days. The histological examinations on the other hand have also shown a significant increase in collagen deposition along with the reduced edema, leukocytes, increased granulation tissue, and fibroblast number in the optimal laser dose treated group compared to the non-illuminated controls.",
author = "Vijendra Prabhu and Rao, {Satish B.S.} and Subhash Chandra and Pramod Kumar and Lakshmi Rao and Vasudeva Guddattu and Kapaettu Satyamoorthy and Mahato, {Krishna K.}",
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T1 - Spectroscopic and histological evaluation of wound healing progression following Low Level Laser Therapy (LLLT)

AU - Prabhu, Vijendra

AU - Rao, Satish B.S.

AU - Chandra, Subhash

AU - Kumar, Pramod

AU - Rao, Lakshmi

AU - Guddattu, Vasudeva

AU - Satyamoorthy, Kapaettu

AU - Mahato, Krishna K.

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N2 - The present study focuses on the evaluation of the effect of He-Ne laser on tissue regeneration by monitoring collagen synthesis in wound granulation tissues in Swiss albino mice using analysis of laser induced fluorescence (LIF) and light microscopy techniques. The spectral analyses of the wound granulation tissues have indicated a dose dependent increase in collagen levels during the post-wounding days. The histological examinations on the other hand have also shown a significant increase in collagen deposition along with the reduced edema, leukocytes, increased granulation tissue, and fibroblast number in the optimal laser dose treated group compared to the non-illuminated controls.

AB - The present study focuses on the evaluation of the effect of He-Ne laser on tissue regeneration by monitoring collagen synthesis in wound granulation tissues in Swiss albino mice using analysis of laser induced fluorescence (LIF) and light microscopy techniques. The spectral analyses of the wound granulation tissues have indicated a dose dependent increase in collagen levels during the post-wounding days. The histological examinations on the other hand have also shown a significant increase in collagen deposition along with the reduced edema, leukocytes, increased granulation tissue, and fibroblast number in the optimal laser dose treated group compared to the non-illuminated controls.

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