Spectrum of complications associated with Plasmodium vivax infection in a tertiary hospital in South-Western India.

Kushal Naha, Sowjanya Dasari, Mukhyaprana Prabhu

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

To determine the range and incidence of complications associated with Plasmodium vivax (P. vivax) malaria. A retrospective analysis was performed of all patients of P. vivax malaria admitted in Kasturba Medical College, Manipal between January and December, 2010. Patients with mixed malarial infection were excluded by appropriate tests. Clinical presentation and laboratory parameters were studied. Medical records of 213 individuals who satisfied the inclusion criteria were reviewed. Anaemia was seen in 65 (30.5%), leucopenia in 38 (17.8%) and thrombocytopenia in 184 (86.4%) patients. Aspartate and alanine aminotransferases were elevated in 86 (40.4%), and 89 (41.9%) patients respectively. Hypoalbuminemia was observed in 157 (73.6%) cases. Elevated serum creatinine was noted in in 59 (27.5%) patients. Creatine kinase was elevated in 30 out of 59 patients (50.8%). Overall, 107 (50.2%) patients fulfilled WHO criteria for severe malaria. None of the patients succumbed to the disease. P. vivax malaria is a potentially severe disease, and the term "benign" tertian malaria is a misnomer. Despite significant morbidity, with timely and appropriate treatment P. vivax malaria has an excellent outcome.

Original languageEnglish
Pages (from-to)79-82
Number of pages4
JournalAsian Pacific Journal of Tropical Medicine
Volume5
Issue number1
DOIs
Publication statusPublished - 01-01-2012

Fingerprint

Plasmodium vivax
Tertiary Care Centers
Malaria
India
Vivax Malaria
Hypoalbuminemia
Leukopenia
Creatine Kinase
Aspartate Aminotransferases
Alanine Transaminase
Coinfection
Thrombocytopenia
Medical Records
Anemia
Creatinine
Morbidity
Incidence

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

@article{1e6ce70d3cb440d0b1ad762960c90dee,
title = "Spectrum of complications associated with Plasmodium vivax infection in a tertiary hospital in South-Western India.",
abstract = "To determine the range and incidence of complications associated with Plasmodium vivax (P. vivax) malaria. A retrospective analysis was performed of all patients of P. vivax malaria admitted in Kasturba Medical College, Manipal between January and December, 2010. Patients with mixed malarial infection were excluded by appropriate tests. Clinical presentation and laboratory parameters were studied. Medical records of 213 individuals who satisfied the inclusion criteria were reviewed. Anaemia was seen in 65 (30.5{\%}), leucopenia in 38 (17.8{\%}) and thrombocytopenia in 184 (86.4{\%}) patients. Aspartate and alanine aminotransferases were elevated in 86 (40.4{\%}), and 89 (41.9{\%}) patients respectively. Hypoalbuminemia was observed in 157 (73.6{\%}) cases. Elevated serum creatinine was noted in in 59 (27.5{\%}) patients. Creatine kinase was elevated in 30 out of 59 patients (50.8{\%}). Overall, 107 (50.2{\%}) patients fulfilled WHO criteria for severe malaria. None of the patients succumbed to the disease. P. vivax malaria is a potentially severe disease, and the term {"}benign{"} tertian malaria is a misnomer. Despite significant morbidity, with timely and appropriate treatment P. vivax malaria has an excellent outcome.",
author = "Kushal Naha and Sowjanya Dasari and Mukhyaprana Prabhu",
year = "2012",
month = "1",
day = "1",
doi = "10.1016/S1995-7645(11)60251-4",
language = "English",
volume = "5",
pages = "79--82",
journal = "Asian Pacific Journal of Tropical Medicine",
issn = "1995-7645",
publisher = "Elsevier (Singapore) Pte Ltd",
number = "1",

}

Spectrum of complications associated with Plasmodium vivax infection in a tertiary hospital in South-Western India. / Naha, Kushal; Dasari, Sowjanya; Prabhu, Mukhyaprana.

In: Asian Pacific Journal of Tropical Medicine, Vol. 5, No. 1, 01.01.2012, p. 79-82.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Spectrum of complications associated with Plasmodium vivax infection in a tertiary hospital in South-Western India.

AU - Naha, Kushal

AU - Dasari, Sowjanya

AU - Prabhu, Mukhyaprana

PY - 2012/1/1

Y1 - 2012/1/1

N2 - To determine the range and incidence of complications associated with Plasmodium vivax (P. vivax) malaria. A retrospective analysis was performed of all patients of P. vivax malaria admitted in Kasturba Medical College, Manipal between January and December, 2010. Patients with mixed malarial infection were excluded by appropriate tests. Clinical presentation and laboratory parameters were studied. Medical records of 213 individuals who satisfied the inclusion criteria were reviewed. Anaemia was seen in 65 (30.5%), leucopenia in 38 (17.8%) and thrombocytopenia in 184 (86.4%) patients. Aspartate and alanine aminotransferases were elevated in 86 (40.4%), and 89 (41.9%) patients respectively. Hypoalbuminemia was observed in 157 (73.6%) cases. Elevated serum creatinine was noted in in 59 (27.5%) patients. Creatine kinase was elevated in 30 out of 59 patients (50.8%). Overall, 107 (50.2%) patients fulfilled WHO criteria for severe malaria. None of the patients succumbed to the disease. P. vivax malaria is a potentially severe disease, and the term "benign" tertian malaria is a misnomer. Despite significant morbidity, with timely and appropriate treatment P. vivax malaria has an excellent outcome.

AB - To determine the range and incidence of complications associated with Plasmodium vivax (P. vivax) malaria. A retrospective analysis was performed of all patients of P. vivax malaria admitted in Kasturba Medical College, Manipal between January and December, 2010. Patients with mixed malarial infection were excluded by appropriate tests. Clinical presentation and laboratory parameters were studied. Medical records of 213 individuals who satisfied the inclusion criteria were reviewed. Anaemia was seen in 65 (30.5%), leucopenia in 38 (17.8%) and thrombocytopenia in 184 (86.4%) patients. Aspartate and alanine aminotransferases were elevated in 86 (40.4%), and 89 (41.9%) patients respectively. Hypoalbuminemia was observed in 157 (73.6%) cases. Elevated serum creatinine was noted in in 59 (27.5%) patients. Creatine kinase was elevated in 30 out of 59 patients (50.8%). Overall, 107 (50.2%) patients fulfilled WHO criteria for severe malaria. None of the patients succumbed to the disease. P. vivax malaria is a potentially severe disease, and the term "benign" tertian malaria is a misnomer. Despite significant morbidity, with timely and appropriate treatment P. vivax malaria has an excellent outcome.

UR - http://www.scopus.com/inward/record.url?scp=84857131992&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84857131992&partnerID=8YFLogxK

U2 - 10.1016/S1995-7645(11)60251-4

DO - 10.1016/S1995-7645(11)60251-4

M3 - Article

C2 - 22182650

AN - SCOPUS:84857131992

VL - 5

SP - 79

EP - 82

JO - Asian Pacific Journal of Tropical Medicine

JF - Asian Pacific Journal of Tropical Medicine

SN - 1995-7645

IS - 1

ER -