Spectrum of H1N1 influenza infection in Indian children

A tertiary centre experience

Kalyan Chakravarthy Konda, Koushik Handattu, Y. Ramesh Bhat, Sandesh B. Kini, Siva G.V. Krishnakanth

Research output: Contribution to journalArticle

Abstract

Objective: To study the clinical profile, severity, outcome and risk factors for H1N1 influenza infection in children < 18 years. Method: Children <18 years admitted to the Paediatric Department of our hospital and confirmed to have H1N1pdm2009 influenza infection from December 2016 to November 2017 were included. We reviewed the case sheets of the study population and captured the required data. Illness was classified as mild, progressive or severe illness and treated as per CDC guidelines. Outcome measures analysed included - mortality, duration of ICU / hospital stay, need for oxygen supplementation or assistive ventilation. Results: Our study involved analysis of 31 children. We found clustering of cases from 1-5 years accounting for 56% with no sex predilection. We observed a bimodal seasonal peak in incidence of infection from December to February (32%) and June to August (42%). Malnutrition was most common risk factor affecting 15/31 (48.4%) children followed by pre-existing medical illness 10/31 (30%). Risk stratification done as per CDC recommended guidelines showed the majority of the children (64.5%) manifesting as mild illness. Chest x-ray showed bilateral non-homogeneous peri-hilar opacities with air bronchogram in 19 (61%) children. Seven (22%) children required admission to ICU, 6 (20%) required oxygen therapy and 1 required noninvasive ventilation. Two children had developed hypotension requiring inotropes. No mortality was observed in the current study. Conclusions: H1N1 Influenza is still causing significant morbidity among children, especially in those with malnutrition and preexisting medical illness.

Original languageEnglish
Pages (from-to)121-126
Number of pages6
JournalSri Lanka Journal of Child Health
Volume49
Issue number2
DOIs
Publication statusPublished - 01-01-2019
Externally publishedYes

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Human Influenza
Infection
Preexisting Condition Coverage
Centers for Disease Control and Prevention (U.S.)
Malnutrition
Guidelines
Oxygen
Noninvasive Ventilation
Mortality
Hospital Departments
Hypotension
Cluster Analysis
Ventilation
Length of Stay
Thorax
Air
X-Rays
Outcome Assessment (Health Care)
Pediatrics
Morbidity

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health

Cite this

Konda, K. C., Handattu, K., Bhat, Y. R., Kini, S. B., & Krishnakanth, S. G. V. (2019). Spectrum of H1N1 influenza infection in Indian children: A tertiary centre experience. Sri Lanka Journal of Child Health, 49(2), 121-126. https://doi.org/10.4038/sljch.v48i2.8704
Konda, Kalyan Chakravarthy ; Handattu, Koushik ; Bhat, Y. Ramesh ; Kini, Sandesh B. ; Krishnakanth, Siva G.V. / Spectrum of H1N1 influenza infection in Indian children : A tertiary centre experience. In: Sri Lanka Journal of Child Health. 2019 ; Vol. 49, No. 2. pp. 121-126.
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Spectrum of H1N1 influenza infection in Indian children : A tertiary centre experience. / Konda, Kalyan Chakravarthy; Handattu, Koushik; Bhat, Y. Ramesh; Kini, Sandesh B.; Krishnakanth, Siva G.V.

In: Sri Lanka Journal of Child Health, Vol. 49, No. 2, 01.01.2019, p. 121-126.

Research output: Contribution to journalArticle

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T2 - A tertiary centre experience

AU - Konda, Kalyan Chakravarthy

AU - Handattu, Koushik

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AU - Kini, Sandesh B.

AU - Krishnakanth, Siva G.V.

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