Spontaneous cerebrospinal fluid rhinorrhea with pneumocephalus

An unusual manifestation of nasal tuberculosis

Waqas Wahid Baig, Mudugundur Vishwareshaya Nagaraja, Muralidhar Varma

Research output: Contribution to journalArticle

Abstract

An unusual case of spontaneous cerebrospinal fluid (CSF) rhinorrhea with a pneumocephalus is described in a middle-aged woman who presented with a watery nasal discharge for 1 week and headache, vomiting, and fever for 1 day. The neurological examination revealed meningeal signs and bilateral papilledema. The CSF picture suggested pyogenic meningitis, and computed tomography of the brain revealed pneumocephalus. Diagnostic nasal endoscopy showed outpouching of the dura from the left olfactory cleft with a CSF leak and granular nasal mucosa. The defect was repaired surgically, and a biopsy of that area revealed granulomatous changes suggestive of tuberculosis. The patient recovered completely with standard four-drug antitubercular therapy. To our knowledge spontaneous CSF rhinorrhea with pneumocephalus occurring secondary to nasal tuberculosis has not been previously reported.

Original languageEnglish
Pages (from-to)350-352
Number of pages3
JournalKorean Journal of Internal Medicine
Volume27
Issue number3
DOIs
Publication statusPublished - 01-09-2012

Fingerprint

Cerebrospinal Fluid Rhinorrhea
Pneumocephalus
Nose
Tuberculosis
Papilledema
Nasal Mucosa
Neurologic Examination
Meningitis
Endoscopy
Vomiting
Headache
Cerebrospinal Fluid
Fever
Tomography
Biopsy
Drug Therapy
Brain

All Science Journal Classification (ASJC) codes

  • Internal Medicine

Cite this

@article{db1c695d07714e94b74535c4a13e5a95,
title = "Spontaneous cerebrospinal fluid rhinorrhea with pneumocephalus: An unusual manifestation of nasal tuberculosis",
abstract = "An unusual case of spontaneous cerebrospinal fluid (CSF) rhinorrhea with a pneumocephalus is described in a middle-aged woman who presented with a watery nasal discharge for 1 week and headache, vomiting, and fever for 1 day. The neurological examination revealed meningeal signs and bilateral papilledema. The CSF picture suggested pyogenic meningitis, and computed tomography of the brain revealed pneumocephalus. Diagnostic nasal endoscopy showed outpouching of the dura from the left olfactory cleft with a CSF leak and granular nasal mucosa. The defect was repaired surgically, and a biopsy of that area revealed granulomatous changes suggestive of tuberculosis. The patient recovered completely with standard four-drug antitubercular therapy. To our knowledge spontaneous CSF rhinorrhea with pneumocephalus occurring secondary to nasal tuberculosis has not been previously reported.",
author = "Baig, {Waqas Wahid} and Nagaraja, {Mudugundur Vishwareshaya} and Muralidhar Varma",
year = "2012",
month = "9",
day = "1",
doi = "10.3904/kjim.2012.27.3.350",
language = "English",
volume = "27",
pages = "350--352",
journal = "Korean Journal of Internal Medicine",
issn = "0494-4712",
publisher = "Korean Association of Internal Medicine",
number = "3",

}

Spontaneous cerebrospinal fluid rhinorrhea with pneumocephalus : An unusual manifestation of nasal tuberculosis. / Baig, Waqas Wahid; Nagaraja, Mudugundur Vishwareshaya; Varma, Muralidhar.

In: Korean Journal of Internal Medicine, Vol. 27, No. 3, 01.09.2012, p. 350-352.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Spontaneous cerebrospinal fluid rhinorrhea with pneumocephalus

T2 - An unusual manifestation of nasal tuberculosis

AU - Baig, Waqas Wahid

AU - Nagaraja, Mudugundur Vishwareshaya

AU - Varma, Muralidhar

PY - 2012/9/1

Y1 - 2012/9/1

N2 - An unusual case of spontaneous cerebrospinal fluid (CSF) rhinorrhea with a pneumocephalus is described in a middle-aged woman who presented with a watery nasal discharge for 1 week and headache, vomiting, and fever for 1 day. The neurological examination revealed meningeal signs and bilateral papilledema. The CSF picture suggested pyogenic meningitis, and computed tomography of the brain revealed pneumocephalus. Diagnostic nasal endoscopy showed outpouching of the dura from the left olfactory cleft with a CSF leak and granular nasal mucosa. The defect was repaired surgically, and a biopsy of that area revealed granulomatous changes suggestive of tuberculosis. The patient recovered completely with standard four-drug antitubercular therapy. To our knowledge spontaneous CSF rhinorrhea with pneumocephalus occurring secondary to nasal tuberculosis has not been previously reported.

AB - An unusual case of spontaneous cerebrospinal fluid (CSF) rhinorrhea with a pneumocephalus is described in a middle-aged woman who presented with a watery nasal discharge for 1 week and headache, vomiting, and fever for 1 day. The neurological examination revealed meningeal signs and bilateral papilledema. The CSF picture suggested pyogenic meningitis, and computed tomography of the brain revealed pneumocephalus. Diagnostic nasal endoscopy showed outpouching of the dura from the left olfactory cleft with a CSF leak and granular nasal mucosa. The defect was repaired surgically, and a biopsy of that area revealed granulomatous changes suggestive of tuberculosis. The patient recovered completely with standard four-drug antitubercular therapy. To our knowledge spontaneous CSF rhinorrhea with pneumocephalus occurring secondary to nasal tuberculosis has not been previously reported.

UR - http://www.scopus.com/inward/record.url?scp=84867073224&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84867073224&partnerID=8YFLogxK

U2 - 10.3904/kjim.2012.27.3.350

DO - 10.3904/kjim.2012.27.3.350

M3 - Article

VL - 27

SP - 350

EP - 352

JO - Korean Journal of Internal Medicine

JF - Korean Journal of Internal Medicine

SN - 0494-4712

IS - 3

ER -