Spot the dot: Solve the mystery: Tsutsugamushi disease

Navin Patil, N. Karthik Rao, Handattu Manjunatha Hande, O. Balaji, Amita, Raghavendra Rao, Kanica Yashi, Talha Ahmed

Research output: Contribution to journalArticle

Abstract

Scrub typhus (Tsutsugamushi disease), is an acute febrile infectious disease endemic in eastern asia is caused by Orienta Tsutsugamushi, transmitted by bite of a Leptotrombidium mite (chigger). 45 year old lady presented with progressive worsening of fever (102F), myalgias, headache and tachycardia (120/min). Leucopenia with thrombocytopenia was noted with elevated liver enzymes. Provisional diagnosis of malaria and dengue was suspected and serological tests were carried out. Paracetamol, IV fluids was given and was patient was monitored for hypotension and bleeding manifestaions. Serology for malaria and dengue were negative. Despite management fever continued to spike. Black eschar was noted on the left shoulder tip and scrub typhus was suspected because of characteristic eschar. Doxycycline was started and serology was positive for Orienta Tsutsugamushi antibodies. Patient recovered with fever and platelet counts normalizing. Recovery was uneventful. The spotting of the "black dot" i.e eschar, helped us in clinching the diagnosis that ultimately lead to the successful and uneventful recovery of this patient. A high index of clinical suspicion, prompt diagnosis and early institution of appropriate antimicrobials can decrease the morbidity and mortality.

Original languageEnglish
Pages (from-to)1752-1755
Number of pages4
JournalResearch Journal of Pharmaceutical, Biological and Chemical Sciences
Volume7
Issue number1
Publication statusPublished - 01-01-2016

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Scrub Typhus
Fever
Trombiculidae
Dengue
Serology
Malaria
Recovery
Doxycycline
Acetaminophen
Platelets
Liver
Metrorrhagia
Far East
Mites
Myalgia
Leukopenia
Serologic Tests
Bites and Stings
Platelet Count
Tachycardia

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Patil, N., Karthik Rao, N., Hande, H. M., Balaji, O., Amita, Rao, R., ... Ahmed, T. (2016). Spot the dot: Solve the mystery: Tsutsugamushi disease. Research Journal of Pharmaceutical, Biological and Chemical Sciences, 7(1), 1752-1755.
Patil, Navin ; Karthik Rao, N. ; Hande, Handattu Manjunatha ; Balaji, O. ; Amita ; Rao, Raghavendra ; Yashi, Kanica ; Ahmed, Talha. / Spot the dot : Solve the mystery: Tsutsugamushi disease. In: Research Journal of Pharmaceutical, Biological and Chemical Sciences. 2016 ; Vol. 7, No. 1. pp. 1752-1755.
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Patil, N, Karthik Rao, N, Hande, HM, Balaji, O, Amita, Rao, R, Yashi, K & Ahmed, T 2016, 'Spot the dot: Solve the mystery: Tsutsugamushi disease', Research Journal of Pharmaceutical, Biological and Chemical Sciences, vol. 7, no. 1, pp. 1752-1755.

Spot the dot : Solve the mystery: Tsutsugamushi disease. / Patil, Navin; Karthik Rao, N.; Hande, Handattu Manjunatha; Balaji, O.; Amita; Rao, Raghavendra; Yashi, Kanica; Ahmed, Talha.

In: Research Journal of Pharmaceutical, Biological and Chemical Sciences, Vol. 7, No. 1, 01.01.2016, p. 1752-1755.

Research output: Contribution to journalArticle

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Patil N, Karthik Rao N, Hande HM, Balaji O, Amita, Rao R et al. Spot the dot: Solve the mystery: Tsutsugamushi disease. Research Journal of Pharmaceutical, Biological and Chemical Sciences. 2016 Jan 1;7(1):1752-1755.