TY - JOUR
T1 - Studies on some N-bridged heterocycles derived from bis- [4-amino-5-mercapto-1,2,4-triazol-3-yl] alkanes
AU - Holla, B. Shivarama
AU - Gonsalves, Richard
AU - Shenoy, Shalini
PY - 1998/8/30
Y1 - 1998/8/30
N2 - A series of bis-[4-amino-5-mercapto-1,2,4-triazol-3-yl] alkanes have been synthesized and were converted into bis-[1,2,4-triazolo[3,4-b]-1,3,4-thiadiazol-4-yl] alkanes. The newly synthesized compounds were characterized by analytical IR, NMR and mass spectral studies. Some of the newly synthesized compounds were screened for their antibacterial properties and exhibited activity with MIC in the range 3-12.5 μg/ml.
AB - A series of bis-[4-amino-5-mercapto-1,2,4-triazol-3-yl] alkanes have been synthesized and were converted into bis-[1,2,4-triazolo[3,4-b]-1,3,4-thiadiazol-4-yl] alkanes. The newly synthesized compounds were characterized by analytical IR, NMR and mass spectral studies. Some of the newly synthesized compounds were screened for their antibacterial properties and exhibited activity with MIC in the range 3-12.5 μg/ml.
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U2 - 10.1016/S0014-827X(98)00068-8
DO - 10.1016/S0014-827X(98)00068-8
M3 - Article
C2 - 10081820
AN - SCOPUS:0032465324
SN - 1860-7179
VL - 53
SP - 574
EP - 578
JO - Farmaco
JF - Farmaco
IS - 8-9
ER -