Studies on some N-bridged heterocycles derived from bis- [4-amino-5-mercapto-1,2,4-triazol-3-yl] alkanes

B. Shivarama Holla, Richard Gonsalves, Shalini Shenoy

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119 Citations (Scopus)

Abstract

A series of bis-[4-amino-5-mercapto-1,2,4-triazol-3-yl] alkanes have been synthesized and were converted into bis-[1,2,4-triazolo[3,4-b]-1,3,4-thiadiazol-4-yl] alkanes. The newly synthesized compounds were characterized by analytical IR, NMR and mass spectral studies. Some of the newly synthesized compounds were screened for their antibacterial properties and exhibited activity with MIC in the range 3-12.5 μg/ml.

Original languageEnglish
Pages (from-to)574-578
Number of pages5
JournalFarmaco
Volume53
Issue number8-9
DOIs
Publication statusPublished - 30-08-1998

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All Science Journal Classification (ASJC) codes

  • Pharmaceutical Science
  • Drug Discovery

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