Studies on the anti-inflammatory and wound healing properties of Moringa oleifera and Aegle marmelos

S. L. Udupa, A. L. Udupa, D. R. Kulkarni

Research output: Contribution to journalArticle

65 Citations (Scopus)

Abstract

The root extracts of M. oleifera (Moringa) and A. marmelos (Bilva) were studied for their anti-inflammatory and wound healing properties. Anti-inflammatory action was studied by observing percent reduction in carrageenin-induced rat paw oedema at 3 h. Wound healing effects were studied on incision (skin breaking strength), excision (percent wound contraction and epithelisation time) and dead space (granuloma breaking strength and biochemical parameters) wound models. Moringa and Bilva showed significant acute antiinflammatory activity. However, only Bilva was able to suppress chronic inflammation significantly. A significant increase in the tensile strength as well as lysyl oxidase activity and hexosamine content were observed in the Moringa treated animals, indicating pro-healing action probably by better cross-linking of collagen. Bilva, on the other hand, was more effective as an anti-inflammatory agent.

Original languageEnglish
Pages (from-to)119-123
Number of pages5
JournalFitoterapia
Volume65
Issue number2
Publication statusPublished - 01-01-1994
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Pharmacology

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    Udupa, S. L., Udupa, A. L., & Kulkarni, D. R. (1994). Studies on the anti-inflammatory and wound healing properties of Moringa oleifera and Aegle marmelos. Fitoterapia, 65(2), 119-123.