Study of cell mediated immunity in malnourished children using DNCB skin sensitization test

B. S. Rai, P. N. Krishnamurthy, B. R. Rao

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

170 malnourished and 30 normal children (controls) were studied for cell-mediated immunity using dinitrochlorobenzene (DNCB) as a skin sensitizer. The Mantoux test was carried out in those who had previously been immunised with BCG vaccination. Tonsillar size and lymphocyte count of the two groups were compared. The results showed that malnourished children developed an impaired reaction to DNCB (45.9%). The reaction to DNCB was related to the degree of malnutrition and to severity of malnutrition. The Mantoux test was negative (91.2%) and tonsillar size was smaller (7.5%) in the malnourished children than in the control group. Lymphopenia was noted in 50.5% of the cases. Thus, malnourished children can be characterised by a definite depletion of the thymolymphatic system.

Original languageEnglish
Pages (from-to)29-33
Number of pages5
JournalIndian Pediatrics
Volume18
Issue number1
Publication statusPublished - 01-12-1981

Fingerprint

Dinitrochlorobenzene
Skin Tests
Cellular Immunity
Malnutrition
Lymphopenia
Lymphocyte Count
Mycobacterium bovis
Vaccination
Control Groups
Skin

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health

Cite this

Rai, B. S., Krishnamurthy, P. N., & Rao, B. R. (1981). Study of cell mediated immunity in malnourished children using DNCB skin sensitization test. Indian Pediatrics, 18(1), 29-33.
Rai, B. S. ; Krishnamurthy, P. N. ; Rao, B. R. / Study of cell mediated immunity in malnourished children using DNCB skin sensitization test. In: Indian Pediatrics. 1981 ; Vol. 18, No. 1. pp. 29-33.
@article{6b11ffeb5ad44592bfb6f1a63e4ebad8,
title = "Study of cell mediated immunity in malnourished children using DNCB skin sensitization test",
abstract = "170 malnourished and 30 normal children (controls) were studied for cell-mediated immunity using dinitrochlorobenzene (DNCB) as a skin sensitizer. The Mantoux test was carried out in those who had previously been immunised with BCG vaccination. Tonsillar size and lymphocyte count of the two groups were compared. The results showed that malnourished children developed an impaired reaction to DNCB (45.9{\%}). The reaction to DNCB was related to the degree of malnutrition and to severity of malnutrition. The Mantoux test was negative (91.2{\%}) and tonsillar size was smaller (7.5{\%}) in the malnourished children than in the control group. Lymphopenia was noted in 50.5{\%} of the cases. Thus, malnourished children can be characterised by a definite depletion of the thymolymphatic system.",
author = "Rai, {B. S.} and Krishnamurthy, {P. N.} and Rao, {B. R.}",
year = "1981",
month = "12",
day = "1",
language = "English",
volume = "18",
pages = "29--33",
journal = "Indian Pediatrics",
issn = "0019-6061",
publisher = "Springer India",
number = "1",

}

Rai, BS, Krishnamurthy, PN & Rao, BR 1981, 'Study of cell mediated immunity in malnourished children using DNCB skin sensitization test', Indian Pediatrics, vol. 18, no. 1, pp. 29-33.

Study of cell mediated immunity in malnourished children using DNCB skin sensitization test. / Rai, B. S.; Krishnamurthy, P. N.; Rao, B. R.

In: Indian Pediatrics, Vol. 18, No. 1, 01.12.1981, p. 29-33.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Study of cell mediated immunity in malnourished children using DNCB skin sensitization test

AU - Rai, B. S.

AU - Krishnamurthy, P. N.

AU - Rao, B. R.

PY - 1981/12/1

Y1 - 1981/12/1

N2 - 170 malnourished and 30 normal children (controls) were studied for cell-mediated immunity using dinitrochlorobenzene (DNCB) as a skin sensitizer. The Mantoux test was carried out in those who had previously been immunised with BCG vaccination. Tonsillar size and lymphocyte count of the two groups were compared. The results showed that malnourished children developed an impaired reaction to DNCB (45.9%). The reaction to DNCB was related to the degree of malnutrition and to severity of malnutrition. The Mantoux test was negative (91.2%) and tonsillar size was smaller (7.5%) in the malnourished children than in the control group. Lymphopenia was noted in 50.5% of the cases. Thus, malnourished children can be characterised by a definite depletion of the thymolymphatic system.

AB - 170 malnourished and 30 normal children (controls) were studied for cell-mediated immunity using dinitrochlorobenzene (DNCB) as a skin sensitizer. The Mantoux test was carried out in those who had previously been immunised with BCG vaccination. Tonsillar size and lymphocyte count of the two groups were compared. The results showed that malnourished children developed an impaired reaction to DNCB (45.9%). The reaction to DNCB was related to the degree of malnutrition and to severity of malnutrition. The Mantoux test was negative (91.2%) and tonsillar size was smaller (7.5%) in the malnourished children than in the control group. Lymphopenia was noted in 50.5% of the cases. Thus, malnourished children can be characterised by a definite depletion of the thymolymphatic system.

UR - http://www.scopus.com/inward/record.url?scp=0019815426&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019815426&partnerID=8YFLogxK

M3 - Article

C2 - 7262994

AN - SCOPUS:0019815426

VL - 18

SP - 29

EP - 33

JO - Indian Pediatrics

JF - Indian Pediatrics

SN - 0019-6061

IS - 1

ER -