Study of protein oxidation products and antioxidants status in primary brain tumor patients

M. Amareshwara, Gayatri M. Rao, M. Rakesh, Ramesh, Sameer, Sreekantha

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Advanced oxidation protein product (AOPP) and protein carbonyl (PC) as protein oxidation products (PPP) and antioxidants such as reduced glutathione (GSH),total thiol (TT) and albumin levels were analyzed in 27 patients with diagnosed primary brain tumor and 25 normal healthy age and sex matched controls. Statistically significant increased (p-0.001) levels of AOPP and PC were noted; GSH and TT levels were increased (p-0.833) & (p-0.032) respectively with decreased albumin levels (p-0.629).Hence increased oxidative stress signified by increased PPP and altered antioxidant levels may have a role in etipathogenesis of primary brain tumor.

Original languageEnglish
Pages (from-to)256-261
Number of pages6
JournalInternational Journal of Pharma and Bio Sciences
Volume2
Issue number1
Publication statusPublished - 01-12-2011

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Advanced Oxidation Protein Products
Brain Neoplasms
Tumors
Brain
Antioxidants
Sulfhydryl Compounds
Oxidation
Albumins
Proteins
Oxidative stress
Glutathione
Oxidative Stress

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Biochemistry
  • Molecular Biology
  • Cell Biology

Cite this

Amareshwara, M. ; Rao, Gayatri M. ; Rakesh, M. ; Ramesh ; Sameer ; Sreekantha. / Study of protein oxidation products and antioxidants status in primary brain tumor patients. In: International Journal of Pharma and Bio Sciences. 2011 ; Vol. 2, No. 1. pp. 256-261.
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Study of protein oxidation products and antioxidants status in primary brain tumor patients. / Amareshwara, M.; Rao, Gayatri M.; Rakesh, M.; Ramesh; Sameer; Sreekantha.

In: International Journal of Pharma and Bio Sciences, Vol. 2, No. 1, 01.12.2011, p. 256-261.

Research output: Contribution to journalArticle

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