Study on occurrence of ESBL and Amp C beta lactamase among gram negative clinical isolates from Government hospital, Mangalore

Neha, Abhisek Routray, Shalini Shenoy

Research output: Contribution to journalArticle

Abstract

Resistant bacteria have emerged and established themselves worldwide as a threat to the favourable outcome of common infections in community and hospital settings. Beta lactamase production by several gram negative and gram positive organisms is perhaps the most important single mechanism of resistance to penicillins and cephalosporins. ESBL and AmpC beta lactamases are typically associated with multiple antibiotic resistances, leaving few therapeutic options. In this study, a total of 116 patient samples were evaluated for occurrence of ESBL and AmpC by Combination disk test and Modified three dimensional test respectively. 58.1% of isolates were ESBL producers, 23.3% were AmpC producers and 15.5% were both ESBL and AmpC producers.

Original languageEnglish
JournalInternational Journal of Pharma and Bio Sciences
Volume5
Issue number3
Publication statusPublished - 01-01-2014

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Cephalosporin Resistance
Penicillin Resistance
Community Hospital
Cephalosporins
beta-Lactamases
Microbial Drug Resistance
Penicillins
Bacteria
Anti-Bacterial Agents
Infection
Therapeutics
AmpC beta-lactamases

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Biochemistry
  • Molecular Biology
  • Cell Biology

Cite this

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