Sublingual misoprostol

A better choice for cervical priming before manual vacuum aspiration

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1 Citation (Scopus)

Abstract

Background: Misoprostol is effective for cervical priming before manual vacuum aspiration (MVA). Aim of study was to determine whether sublingual misoprostol with a shorter interval of 2 hours before MVA would be as effective as its standard vaginal administration. Study Design: This randomized control trial included 82 women randomly assigned to receive 400 mcg of misoprostol, either sublingually or vaginally. MVA was performed 2 hours and 3 hours after in sublingual and vaginal group, respectively. Results: Cervical dilatation of 8 mm was achieved within 2 hours in sublingual group. Mean time taken for procedure (14.4 5.3: sublingual group and 16.2 5.7: vaginal group), and blood loss was comparable (12.2 9.7 ml in sublingual group and 13.7 8.5 ml in vaginal group). Conclusion: 2 hour of cervical priming with 400 mcg of sublingual misoprostol before MVA was as good as 3 hours with vaginal administration of the same dose.

Original languageEnglish
Pages (from-to)356-362
Number of pages7
JournalIndian Journal of Medical Sciences
Volume64
Issue number8
DOIs
Publication statusPublished - 01-08-2010

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Misoprostol
Vacuum
Intravaginal Administration
First Labor Stage
Blood Group Antigens

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

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title = "Sublingual misoprostol: A better choice for cervical priming before manual vacuum aspiration",
abstract = "Background: Misoprostol is effective for cervical priming before manual vacuum aspiration (MVA). Aim of study was to determine whether sublingual misoprostol with a shorter interval of 2 hours before MVA would be as effective as its standard vaginal administration. Study Design: This randomized control trial included 82 women randomly assigned to receive 400 mcg of misoprostol, either sublingually or vaginally. MVA was performed 2 hours and 3 hours after in sublingual and vaginal group, respectively. Results: Cervical dilatation of 8 mm was achieved within 2 hours in sublingual group. Mean time taken for procedure (14.4 5.3: sublingual group and 16.2 5.7: vaginal group), and blood loss was comparable (12.2 9.7 ml in sublingual group and 13.7 8.5 ml in vaginal group). Conclusion: 2 hour of cervical priming with 400 mcg of sublingual misoprostol before MVA was as good as 3 hours with vaginal administration of the same dose.",
author = "J. Shetty and R. Chawla and D. Pandey and A. Kamath and V. Guddattu",
year = "2010",
month = "8",
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TY - JOUR

T1 - Sublingual misoprostol

T2 - A better choice for cervical priming before manual vacuum aspiration

AU - Shetty, J.

AU - Chawla, R.

AU - Pandey, D.

AU - Kamath, A.

AU - Guddattu, V.

PY - 2010/8/1

Y1 - 2010/8/1

N2 - Background: Misoprostol is effective for cervical priming before manual vacuum aspiration (MVA). Aim of study was to determine whether sublingual misoprostol with a shorter interval of 2 hours before MVA would be as effective as its standard vaginal administration. Study Design: This randomized control trial included 82 women randomly assigned to receive 400 mcg of misoprostol, either sublingually or vaginally. MVA was performed 2 hours and 3 hours after in sublingual and vaginal group, respectively. Results: Cervical dilatation of 8 mm was achieved within 2 hours in sublingual group. Mean time taken for procedure (14.4 5.3: sublingual group and 16.2 5.7: vaginal group), and blood loss was comparable (12.2 9.7 ml in sublingual group and 13.7 8.5 ml in vaginal group). Conclusion: 2 hour of cervical priming with 400 mcg of sublingual misoprostol before MVA was as good as 3 hours with vaginal administration of the same dose.

AB - Background: Misoprostol is effective for cervical priming before manual vacuum aspiration (MVA). Aim of study was to determine whether sublingual misoprostol with a shorter interval of 2 hours before MVA would be as effective as its standard vaginal administration. Study Design: This randomized control trial included 82 women randomly assigned to receive 400 mcg of misoprostol, either sublingually or vaginally. MVA was performed 2 hours and 3 hours after in sublingual and vaginal group, respectively. Results: Cervical dilatation of 8 mm was achieved within 2 hours in sublingual group. Mean time taken for procedure (14.4 5.3: sublingual group and 16.2 5.7: vaginal group), and blood loss was comparable (12.2 9.7 ml in sublingual group and 13.7 8.5 ml in vaginal group). Conclusion: 2 hour of cervical priming with 400 mcg of sublingual misoprostol before MVA was as good as 3 hours with vaginal administration of the same dose.

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