Success stories in genomic medicine from resource-limited countries

Konstantinos Mitropoulos, Hayat Al Jaibeji, Diego A. Forero, Paul Laissue, Ambroise Wonkam, Catalina Lopez-Correa, Zahurin Mohamed, Wasun Chantratita, Ming Ta Michael Lee, Adrian Llerena, Angela Brand, Bassam R. Ali, George P. Patrinos

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

In recent years, the translation of genomic discoveries into mainstream medical practice and public health has gained momentum, facilitated by the advent of new technologies. However, there are often major discrepancies in the pace of implementation of genomic medicine between developed and developing/resource-limited countries. The main reason does not only lie in the limitation of resources but also in the slow pace of adoption of the new findings and the poor understanding of the potential that this new discipline offers to rationalize medical diagnosis and treatment. Here, we present and critically discuss examples from the successful implementation of genomic medicine in resource-limited countries, focusing on pharmacogenomics, genome informatics, and public health genomics, emphasizing in the latter case genomic education, stakeholder analysis, and economics in pharmacogenomics. These examples can be considered as model cases and be readily replicated for the wide implementation of pharmacogenomics and genomic medicine in other resource-limited environments.

Original languageEnglish
Article number11
JournalHuman Genomics
Volume9
Issue number1
DOIs
Publication statusPublished - 2015

Fingerprint

Pharmacogenetics
Medicine
Public Health Informatics
Public Health Practice
Genomics
Economics
Genome
Technology
Education

All Science Journal Classification (ASJC) codes

  • Molecular Medicine
  • Molecular Biology
  • Genetics
  • Drug Discovery

Cite this

Mitropoulos, K., Al Jaibeji, H., Forero, D. A., Laissue, P., Wonkam, A., Lopez-Correa, C., ... Patrinos, G. P. (2015). Success stories in genomic medicine from resource-limited countries. Human Genomics, 9(1), [11]. https://doi.org/10.1186/s40246-015-0033-3
Mitropoulos, Konstantinos ; Al Jaibeji, Hayat ; Forero, Diego A. ; Laissue, Paul ; Wonkam, Ambroise ; Lopez-Correa, Catalina ; Mohamed, Zahurin ; Chantratita, Wasun ; Lee, Ming Ta Michael ; Llerena, Adrian ; Brand, Angela ; Ali, Bassam R. ; Patrinos, George P. / Success stories in genomic medicine from resource-limited countries. In: Human Genomics. 2015 ; Vol. 9, No. 1.
@article{508be939fe2d451ea742d14065b61c8d,
title = "Success stories in genomic medicine from resource-limited countries",
abstract = "In recent years, the translation of genomic discoveries into mainstream medical practice and public health has gained momentum, facilitated by the advent of new technologies. However, there are often major discrepancies in the pace of implementation of genomic medicine between developed and developing/resource-limited countries. The main reason does not only lie in the limitation of resources but also in the slow pace of adoption of the new findings and the poor understanding of the potential that this new discipline offers to rationalize medical diagnosis and treatment. Here, we present and critically discuss examples from the successful implementation of genomic medicine in resource-limited countries, focusing on pharmacogenomics, genome informatics, and public health genomics, emphasizing in the latter case genomic education, stakeholder analysis, and economics in pharmacogenomics. These examples can be considered as model cases and be readily replicated for the wide implementation of pharmacogenomics and genomic medicine in other resource-limited environments.",
author = "Konstantinos Mitropoulos and {Al Jaibeji}, Hayat and Forero, {Diego A.} and Paul Laissue and Ambroise Wonkam and Catalina Lopez-Correa and Zahurin Mohamed and Wasun Chantratita and Lee, {Ming Ta Michael} and Adrian Llerena and Angela Brand and Ali, {Bassam R.} and Patrinos, {George P.}",
year = "2015",
doi = "10.1186/s40246-015-0033-3",
language = "English",
volume = "9",
journal = "Human Genomics",
issn = "1473-9542",
publisher = "Henry Stewart Publications",
number = "1",

}

Mitropoulos, K, Al Jaibeji, H, Forero, DA, Laissue, P, Wonkam, A, Lopez-Correa, C, Mohamed, Z, Chantratita, W, Lee, MTM, Llerena, A, Brand, A, Ali, BR & Patrinos, GP 2015, 'Success stories in genomic medicine from resource-limited countries', Human Genomics, vol. 9, no. 1, 11. https://doi.org/10.1186/s40246-015-0033-3

Success stories in genomic medicine from resource-limited countries. / Mitropoulos, Konstantinos; Al Jaibeji, Hayat; Forero, Diego A.; Laissue, Paul; Wonkam, Ambroise; Lopez-Correa, Catalina; Mohamed, Zahurin; Chantratita, Wasun; Lee, Ming Ta Michael; Llerena, Adrian; Brand, Angela; Ali, Bassam R.; Patrinos, George P.

In: Human Genomics, Vol. 9, No. 1, 11, 2015.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Success stories in genomic medicine from resource-limited countries

AU - Mitropoulos, Konstantinos

AU - Al Jaibeji, Hayat

AU - Forero, Diego A.

AU - Laissue, Paul

AU - Wonkam, Ambroise

AU - Lopez-Correa, Catalina

AU - Mohamed, Zahurin

AU - Chantratita, Wasun

AU - Lee, Ming Ta Michael

AU - Llerena, Adrian

AU - Brand, Angela

AU - Ali, Bassam R.

AU - Patrinos, George P.

PY - 2015

Y1 - 2015

N2 - In recent years, the translation of genomic discoveries into mainstream medical practice and public health has gained momentum, facilitated by the advent of new technologies. However, there are often major discrepancies in the pace of implementation of genomic medicine between developed and developing/resource-limited countries. The main reason does not only lie in the limitation of resources but also in the slow pace of adoption of the new findings and the poor understanding of the potential that this new discipline offers to rationalize medical diagnosis and treatment. Here, we present and critically discuss examples from the successful implementation of genomic medicine in resource-limited countries, focusing on pharmacogenomics, genome informatics, and public health genomics, emphasizing in the latter case genomic education, stakeholder analysis, and economics in pharmacogenomics. These examples can be considered as model cases and be readily replicated for the wide implementation of pharmacogenomics and genomic medicine in other resource-limited environments.

AB - In recent years, the translation of genomic discoveries into mainstream medical practice and public health has gained momentum, facilitated by the advent of new technologies. However, there are often major discrepancies in the pace of implementation of genomic medicine between developed and developing/resource-limited countries. The main reason does not only lie in the limitation of resources but also in the slow pace of adoption of the new findings and the poor understanding of the potential that this new discipline offers to rationalize medical diagnosis and treatment. Here, we present and critically discuss examples from the successful implementation of genomic medicine in resource-limited countries, focusing on pharmacogenomics, genome informatics, and public health genomics, emphasizing in the latter case genomic education, stakeholder analysis, and economics in pharmacogenomics. These examples can be considered as model cases and be readily replicated for the wide implementation of pharmacogenomics and genomic medicine in other resource-limited environments.

UR - http://www.scopus.com/inward/record.url?scp=84944895937&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84944895937&partnerID=8YFLogxK

U2 - 10.1186/s40246-015-0033-3

DO - 10.1186/s40246-015-0033-3

M3 - Article

C2 - 26081768

AN - SCOPUS:84944895937

VL - 9

JO - Human Genomics

JF - Human Genomics

SN - 1473-9542

IS - 1

M1 - 11

ER -

Mitropoulos K, Al Jaibeji H, Forero DA, Laissue P, Wonkam A, Lopez-Correa C et al. Success stories in genomic medicine from resource-limited countries. Human Genomics. 2015;9(1). 11. https://doi.org/10.1186/s40246-015-0033-3