TY - JOUR
T1 - Success stories in genomic medicine from resource-limited countries
AU - Mitropoulos, Konstantinos
AU - Al Jaibeji, Hayat
AU - Forero, Diego A.
AU - Laissue, Paul
AU - Wonkam, Ambroise
AU - Lopez-Correa, Catalina
AU - Mohamed, Zahurin
AU - Chantratita, Wasun
AU - Lee, Ming Ta Michael
AU - Llerena, Adrian
AU - Brand, Angela
AU - Ali, Bassam R.
AU - Patrinos, George P.
N1 - Funding Information:
KM is scientific advisor of the Golden Helix Foundation. AB, MTML, and GPP are members of the Scientific Advisory Committee of the Genomic Medicine Alliance. DAF is supported by research grants from Colciencias and VCTI-UAN. The authors declare that they have no competing interests.
Publisher Copyright:
© 2015 Mitropoulos et al.
PY - 2015
Y1 - 2015
N2 - In recent years, the translation of genomic discoveries into mainstream medical practice and public health has gained momentum, facilitated by the advent of new technologies. However, there are often major discrepancies in the pace of implementation of genomic medicine between developed and developing/resource-limited countries. The main reason does not only lie in the limitation of resources but also in the slow pace of adoption of the new findings and the poor understanding of the potential that this new discipline offers to rationalize medical diagnosis and treatment. Here, we present and critically discuss examples from the successful implementation of genomic medicine in resource-limited countries, focusing on pharmacogenomics, genome informatics, and public health genomics, emphasizing in the latter case genomic education, stakeholder analysis, and economics in pharmacogenomics. These examples can be considered as model cases and be readily replicated for the wide implementation of pharmacogenomics and genomic medicine in other resource-limited environments.
AB - In recent years, the translation of genomic discoveries into mainstream medical practice and public health has gained momentum, facilitated by the advent of new technologies. However, there are often major discrepancies in the pace of implementation of genomic medicine between developed and developing/resource-limited countries. The main reason does not only lie in the limitation of resources but also in the slow pace of adoption of the new findings and the poor understanding of the potential that this new discipline offers to rationalize medical diagnosis and treatment. Here, we present and critically discuss examples from the successful implementation of genomic medicine in resource-limited countries, focusing on pharmacogenomics, genome informatics, and public health genomics, emphasizing in the latter case genomic education, stakeholder analysis, and economics in pharmacogenomics. These examples can be considered as model cases and be readily replicated for the wide implementation of pharmacogenomics and genomic medicine in other resource-limited environments.
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U2 - 10.1186/s40246-015-0033-3
DO - 10.1186/s40246-015-0033-3
M3 - Article
C2 - 26081768
AN - SCOPUS:84944895937
SN - 1473-9542
VL - 9
JO - Human Genomics
JF - Human Genomics
IS - 1
M1 - 11
ER -
