Successful treatment of vincristine induced ptosis and polyneuropathy with pyridoxine and pyridostigmine in a child with acute lymphoblastic leukemia

Kamalakshi G. Bhat; Vikram Singhal; Anupama S. Borker

doi:10.4103/0971-5851.103152

Successful treatment of vincristine induced ptosis and polyneuropathy with pyridoxine and pyridostigmine in a child with acute lymphoblastic leukemia

Kamalakshi G. Bhat, Vikram Singhal, Anupama S. Borker

Department of Paediatrics, Kasturba Medical College, Mangalore

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

Vincristine is used in the treatment of solid tumors, lymphoma and leukemia in children. The dose-limiting toxicity is its neurotoxicity. We describe a 2-year-old girl with acute lymphoblastic leukemia who developed vincristine-induced polyneuropathy with bilateral ptosis and recovered on treatment with pyridoxine and pyridostigmine.

Original language	English
Pages (from-to)	185-187
Number of pages	3
Journal	Indian Journal of Medical and Paediatric Oncology
Volume	33
Issue number	3
DOIs	https://doi.org/10.4103/0971-5851.103152
Publication status	Published - 07-2012

All Science Journal Classification (ASJC) codes

Oncology
Pediatrics, Perinatology, and Child Health

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abstract = "Vincristine is used in the treatment of solid tumors, lymphoma and leukemia in children. The dose-limiting toxicity is its neurotoxicity. We describe a 2-year-old girl with acute lymphoblastic leukemia who developed vincristine-induced polyneuropathy with bilateral ptosis and recovered on treatment with pyridoxine and pyridostigmine.",

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AU - Singhal, Vikram

AU - Borker, Anupama S.

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N2 - Vincristine is used in the treatment of solid tumors, lymphoma and leukemia in children. The dose-limiting toxicity is its neurotoxicity. We describe a 2-year-old girl with acute lymphoblastic leukemia who developed vincristine-induced polyneuropathy with bilateral ptosis and recovered on treatment with pyridoxine and pyridostigmine.

AB - Vincristine is used in the treatment of solid tumors, lymphoma and leukemia in children. The dose-limiting toxicity is its neurotoxicity. We describe a 2-year-old girl with acute lymphoblastic leukemia who developed vincristine-induced polyneuropathy with bilateral ptosis and recovered on treatment with pyridoxine and pyridostigmine.

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Successful treatment of vincristine induced ptosis and polyneuropathy with pyridoxine and pyridostigmine in a child with acute lymphoblastic leukemia

Abstract

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