Abstract

The worldwide emergence of NDM-1 positive, multiresistant Enterobacteriacae have created a major global health problem. The NDM-1 can catalyze the hydrolysis of a various antibiotics including the latest generation carbapenems, which are often referred as the last line of antibiotics active against multiresistant gram-negative pathogens. Also there are few antiobiotics in pipeline active against gram-negative microbes and none that are active against NDM-1; presents a serious threat to antibiotics therapy. We are suggesting a rational use of antibiotics with an implementation of stringent policy for the prescription of antibiotics especially in the developing countries where antibiotics abuse is more common. The World Health Organization should also issue a guideline pertaining to NDM-1 positive, multiresistant Enerobacteriacae.

Original languageEnglish
Pages (from-to)1183-1187
Number of pages5
JournalDer Pharmacia Lettre
Volume4
Issue number4
Publication statusPublished - 2012

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Anti-Bacterial Agents
Carbapenems
Developing Countries
Prescriptions
Global Health
Hydrolysis
Guidelines
Therapeutics

All Science Journal Classification (ASJC) codes

  • Pharmaceutical Science

Cite this

Suthar, Sharad Kumar ; Joseph, Alex ; Lohan, Sandeep ; Alex, Angel Treasa. / Superbug NDM-1 : A global health problem. In: Der Pharmacia Lettre. 2012 ; Vol. 4, No. 4. pp. 1183-1187.
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Suthar, SK, Joseph, A, Lohan, S & Alex, AT 2012, 'Superbug NDM-1: A global health problem', Der Pharmacia Lettre, vol. 4, no. 4, pp. 1183-1187.

Superbug NDM-1 : A global health problem. / Suthar, Sharad Kumar; Joseph, Alex; Lohan, Sandeep; Alex, Angel Treasa.

In: Der Pharmacia Lettre, Vol. 4, No. 4, 2012, p. 1183-1187.

Research output: Contribution to journalArticle

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