Surgical treatment of medically refractory epilepsy

K. Radhakrishnan, G. Menon

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The last two decades have witnessed remarkable advances in the evaluation and treatment of patients with refractory epilepsy. We now understand the natural history of epilepsy and the causes of medical refractoriness better. The improvement in the localization of the seizure focus through the advances in technology such as digital EEG, structural and functional neuroimaging and stereotactic placement of invasive electrodes have facilitated the selection of ideal surgical candidates and thereby have improved postoperative outcome. A recent randomized, controlled trial confirmed that the seizure outcome is far superior in surgically-treated refractory temporal lobe epilepsy patients when compared to those continued on medical treatment. Today, surgical treatment is certainly a cost-effective option in carefully selected patients with medically refractory partial epilepsy. Developing countries should concentrate on selectively utilizing the recent advances to evolve cost-effective epilepsy surgery programs. It is encouraging to note that more neurology centers in India and other developing nations are currently developing facilities for epilepsy surgery.
Original languageEnglish
Pages (from-to)707-719
Number of pages13
JournalCurrent Science
Volume82
Issue number6
Publication statusPublished - 2002

Fingerprint

Epilepsy
Developing Countries
Seizures
Costs and Cost Analysis
Functional Neuroimaging
Partial Epilepsy
Temporal Lobe Epilepsy
Therapeutics
Neurology
India
Electroencephalography
Electrodes
Randomized Controlled Trials
Technology

Cite this

Radhakrishnan, K. ; Menon, G. / Surgical treatment of medically refractory epilepsy. In: Current Science. 2002 ; Vol. 82, No. 6. pp. 707-719.
@article{ddec4018b203439994cbd814632cf043,
title = "Surgical treatment of medically refractory epilepsy",
abstract = "The last two decades have witnessed remarkable advances in the evaluation and treatment of patients with refractory epilepsy. We now understand the natural history of epilepsy and the causes of medical refractoriness better. The improvement in the localization of the seizure focus through the advances in technology such as digital EEG, structural and functional neuroimaging and stereotactic placement of invasive electrodes have facilitated the selection of ideal surgical candidates and thereby have improved postoperative outcome. A recent randomized, controlled trial confirmed that the seizure outcome is far superior in surgically-treated refractory temporal lobe epilepsy patients when compared to those continued on medical treatment. Today, surgical treatment is certainly a cost-effective option in carefully selected patients with medically refractory partial epilepsy. Developing countries should concentrate on selectively utilizing the recent advances to evolve cost-effective epilepsy surgery programs. It is encouraging to note that more neurology centers in India and other developing nations are currently developing facilities for epilepsy surgery.",
author = "K. Radhakrishnan and G. Menon",
note = "cited By 2",
year = "2002",
language = "English",
volume = "82",
pages = "707--719",
journal = "Current Science",
issn = "0011-3891",
publisher = "Indian Academy of Sciences",
number = "6",

}

Radhakrishnan, K & Menon, G 2002, 'Surgical treatment of medically refractory epilepsy', Current Science, vol. 82, no. 6, pp. 707-719.

Surgical treatment of medically refractory epilepsy. / Radhakrishnan, K.; Menon, G.

In: Current Science, Vol. 82, No. 6, 2002, p. 707-719.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Surgical treatment of medically refractory epilepsy

AU - Radhakrishnan, K.

AU - Menon, G.

N1 - cited By 2

PY - 2002

Y1 - 2002

N2 - The last two decades have witnessed remarkable advances in the evaluation and treatment of patients with refractory epilepsy. We now understand the natural history of epilepsy and the causes of medical refractoriness better. The improvement in the localization of the seizure focus through the advances in technology such as digital EEG, structural and functional neuroimaging and stereotactic placement of invasive electrodes have facilitated the selection of ideal surgical candidates and thereby have improved postoperative outcome. A recent randomized, controlled trial confirmed that the seizure outcome is far superior in surgically-treated refractory temporal lobe epilepsy patients when compared to those continued on medical treatment. Today, surgical treatment is certainly a cost-effective option in carefully selected patients with medically refractory partial epilepsy. Developing countries should concentrate on selectively utilizing the recent advances to evolve cost-effective epilepsy surgery programs. It is encouraging to note that more neurology centers in India and other developing nations are currently developing facilities for epilepsy surgery.

AB - The last two decades have witnessed remarkable advances in the evaluation and treatment of patients with refractory epilepsy. We now understand the natural history of epilepsy and the causes of medical refractoriness better. The improvement in the localization of the seizure focus through the advances in technology such as digital EEG, structural and functional neuroimaging and stereotactic placement of invasive electrodes have facilitated the selection of ideal surgical candidates and thereby have improved postoperative outcome. A recent randomized, controlled trial confirmed that the seizure outcome is far superior in surgically-treated refractory temporal lobe epilepsy patients when compared to those continued on medical treatment. Today, surgical treatment is certainly a cost-effective option in carefully selected patients with medically refractory partial epilepsy. Developing countries should concentrate on selectively utilizing the recent advances to evolve cost-effective epilepsy surgery programs. It is encouraging to note that more neurology centers in India and other developing nations are currently developing facilities for epilepsy surgery.

M3 - Article

VL - 82

SP - 707

EP - 719

JO - Current Science

JF - Current Science

SN - 0011-3891

IS - 6

ER -