Synthesis and anti-inflammatory activity of substituted (E)-4-phenyl-3-buten-2-ones

G. Elias, M.N.A. Rao

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Abstract

A series of ring substituted 4-phenyl-3-buten-2-ones was synthesized and evaluated for anti-inflammatory activity by carrageenan-induced paw edema in rats. Several compounds showed significant activity, among them, the 4-acetyloxy-3-methoxy derivative was the most active and the 4-methoxy derivatives were the least effective. © 1988.
Original languageUndefined/Unknown
Pages (from-to)379-380
Number of pages2
JournalEuropean Journal of Medicinal Chemistry
Volume23
Issue number4
DOIs
Publication statusPublished - 1988
Externally publishedYes

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