Synthesis and antibacterial activity of some 2,3-disubstituted quinazolin-4(3H) ones

V. Dinakaran, H. Unnissa, E. Kalishwari

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Some new 2,3-disubstituted quinazolin-4-(3H)-ones have been synthesized by the condensation of respective 2-substituted 1,3-benzoxazin-4-ones (4a-b) with different primary amines in equimolar conc. The structures of these compounds have been established on the basis of their elemental, analytical and spectral data. These compounds were tested for invitro antibacterial activity against Staphylococcus aureus (ATCC 9144), Staphylococcus epidermidis (ATCC 155), Micrococcus luteus (ATCC 8341), Klebsiella pneumoniae (ATCC 29665) and Escherichia coli (ATCC 25922).
Original languageEnglish
Pages (from-to)347-350
Number of pages4
JournalIndian Journal of Heterocyclic Chemistry
Issue number4
Publication statusPublished - 2008


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