Synthesis and antitubercular activity of Mannich bases of 2-methyl-3H-quinazolin-4-ones

P. Nandy, M.T. Vishalakshi, A.R. Bhat

Research output: Contribution to journalArticle

51 Citations (Scopus)

Abstract

Condensation of 2 with formaldehyde and 2-methyl-3H-quinazolin-4-one 3 yielded Mannich bases 2-methyl-3-[(2-aminomethyl) benzothiazolyl] quinazolin-4-ones 4(a-d). The synthesized compounds were screened for their antitubercular activity against Mycobacterium tuberculosis H37Rv strain and their structures were confirmed by spectral and elemental analysis data.
Original languageEnglish
Pages (from-to)293-294
Number of pages2
JournalIndian Journal of Heterocyclic Chemistry
Volume15
Issue number3
Publication statusPublished - 2006
Externally publishedYes

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