Condensation of 2 with formaldehyde and 2-methyl-3H-quinazolin-4-one 3 yielded Mannich bases 2-methyl-3-[(2-aminomethyl) benzothiazolyl] quinazolin-4-ones 4(a-d). The synthesized compounds were screened for their antitubercular activity against Mycobacterium tuberculosis H37Rv strain and their structures were confirmed by spectral and elemental analysis data.
|Number of pages||2|
|Journal||Indian Journal of Heterocyclic Chemistry|
|Publication status||Published - 2006|
Nandy, P., Vishalakshi, M. T., & Bhat, A. R. (2006). Synthesis and antitubercular activity of Mannich bases of 2-methyl-3H-quinazolin-4-ones. Indian Journal of Heterocyclic Chemistry, 15(3), 293-294. https://www.scopus.com/inward/record.uri?eid=2-s2.0-33747797083&partnerID=40&md5=e71ece6ed4e8ebce925122620b81eb22