Synthesis and biological activity of 1,2,4-triazole derivatives containing triazolo-thiadiazole and triazolo-thiadiazolidine ring systems

R.H. Udupi, P. Purushottamachar, A.R. Bhat

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Various 3-substituted-5-pyridyl-1,2,4-triazolo (3,4-b) (1,3,4) thiadiazoles (4a-I) and 4-pyridoyl-3-substituted-5-thiono-1,2,4-triazolo (3,4-b) (1,3,4) thiadiazolidines (5a-I) were synthesized by the reaction of 4-(N-pyridyl carboxamido)-5-mercapto-3-substituted-1,2,4-triazoles (3a-I) with concentrated sulphuric acid and carbon disulphide respectively. These compounds were screened for their antimicrobial activities.
Original languageEnglish
Pages (from-to)291-294
Number of pages4
JournalIndian Journal of Heterocyclic Chemistry
Volume9
Issue number4
Publication statusPublished - 2000
Externally publishedYes

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Thiadiazoles
Carbon Disulfide
Bioactivity
Derivatives
Acids
1,3,4-thiadiazole
1,2,4-triazole

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title = "Synthesis and biological activity of 1,2,4-triazole derivatives containing triazolo-thiadiazole and triazolo-thiadiazolidine ring systems",
abstract = "Various 3-substituted-5-pyridyl-1,2,4-triazolo (3,4-b) (1,3,4) thiadiazoles (4a-I) and 4-pyridoyl-3-substituted-5-thiono-1,2,4-triazolo (3,4-b) (1,3,4) thiadiazolidines (5a-I) were synthesized by the reaction of 4-(N-pyridyl carboxamido)-5-mercapto-3-substituted-1,2,4-triazoles (3a-I) with concentrated sulphuric acid and carbon disulphide respectively. These compounds were screened for their antimicrobial activities.",
author = "R.H. Udupi and P. Purushottamachar and A.R. Bhat",
note = "Cited By :2 Export Date: 10 November 2017 Correspondence Address: Udupi, R.H.; Dept. of Pharmaceutical Chemistry, V.L. College of Pharmacy, Raichur-584 101, India References: Dreikorn, B.A., Thibault, T.D., (1977) Chem. Abstr., 86, pp. 166387g. , U.S. Pat., 4,322,008 (1977); Srivastava, V., Sen, S., Shekar, R., (1994) Indian J. Chem., 38 B, p. 344; Hosur, M.C., Talwar, M.B., Laddi, U.V., Bennur, R.S., Bennur, S.C., (1995) Indian J. Chem., 34 B, p. 707; Hussain, M.I., Amir, M., (1986) J. Indian Chem. Soc., 63, p. 317; Omar, A., Mohsen, M.E., Aboul, W., Omaima, M., (1986) J. Heterocyclic Chem., 23, p. 1339; Rich, S., Horsfall, J.G., (1952) Phytopathology, 42, p. 457; Cruickshank, R., Duguid, J.P., Marmoin, B.P., Swain, H.A., (1975) {"}The Practice of Medical Microbiology{"}, Vol II, 12th Ed, 2. , Churchill Livingstone; Reid, J.R., Heindel, N.D., (1976) J. Heterocyclic Chem., 13, p. 925",
year = "2000",
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journal = "Indian Journal of Heterocyclic Chemistry",
issn = "0971-1627",
publisher = "National Academy of Chemistry",
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Synthesis and biological activity of 1,2,4-triazole derivatives containing triazolo-thiadiazole and triazolo-thiadiazolidine ring systems. / Udupi, R.H.; Purushottamachar, P.; Bhat, A.R.

In: Indian Journal of Heterocyclic Chemistry, Vol. 9, No. 4, 2000, p. 291-294.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Synthesis and biological activity of 1,2,4-triazole derivatives containing triazolo-thiadiazole and triazolo-thiadiazolidine ring systems

AU - Udupi, R.H.

AU - Purushottamachar, P.

AU - Bhat, A.R.

N1 - Cited By :2 Export Date: 10 November 2017 Correspondence Address: Udupi, R.H.; Dept. of Pharmaceutical Chemistry, V.L. College of Pharmacy, Raichur-584 101, India References: Dreikorn, B.A., Thibault, T.D., (1977) Chem. Abstr., 86, pp. 166387g. , U.S. Pat., 4,322,008 (1977); Srivastava, V., Sen, S., Shekar, R., (1994) Indian J. Chem., 38 B, p. 344; Hosur, M.C., Talwar, M.B., Laddi, U.V., Bennur, R.S., Bennur, S.C., (1995) Indian J. Chem., 34 B, p. 707; Hussain, M.I., Amir, M., (1986) J. Indian Chem. Soc., 63, p. 317; Omar, A., Mohsen, M.E., Aboul, W., Omaima, M., (1986) J. Heterocyclic Chem., 23, p. 1339; Rich, S., Horsfall, J.G., (1952) Phytopathology, 42, p. 457; Cruickshank, R., Duguid, J.P., Marmoin, B.P., Swain, H.A., (1975) "The Practice of Medical Microbiology", Vol II, 12th Ed, 2. , Churchill Livingstone; Reid, J.R., Heindel, N.D., (1976) J. Heterocyclic Chem., 13, p. 925

PY - 2000

Y1 - 2000

N2 - Various 3-substituted-5-pyridyl-1,2,4-triazolo (3,4-b) (1,3,4) thiadiazoles (4a-I) and 4-pyridoyl-3-substituted-5-thiono-1,2,4-triazolo (3,4-b) (1,3,4) thiadiazolidines (5a-I) were synthesized by the reaction of 4-(N-pyridyl carboxamido)-5-mercapto-3-substituted-1,2,4-triazoles (3a-I) with concentrated sulphuric acid and carbon disulphide respectively. These compounds were screened for their antimicrobial activities.

AB - Various 3-substituted-5-pyridyl-1,2,4-triazolo (3,4-b) (1,3,4) thiadiazoles (4a-I) and 4-pyridoyl-3-substituted-5-thiono-1,2,4-triazolo (3,4-b) (1,3,4) thiadiazolidines (5a-I) were synthesized by the reaction of 4-(N-pyridyl carboxamido)-5-mercapto-3-substituted-1,2,4-triazoles (3a-I) with concentrated sulphuric acid and carbon disulphide respectively. These compounds were screened for their antimicrobial activities.

M3 - Article

VL - 9

SP - 291

EP - 294

JO - Indian Journal of Heterocyclic Chemistry

JF - Indian Journal of Heterocyclic Chemistry

SN - 0971-1627

IS - 4

ER -