The hydrazide of 2-(6-methoxy α-naphthyl)-propionic acid (Naproxen) was converted to the Schiff's bases which in turn on reacting with aryl and aryloxy acetyl chlorides yielded the corresponding azetidin-2-ones (4-a-c and 5 a-t). Representative compounds screened for antitubercular activity were proved to be equipotent with streptomycin.
|Number of pages||4|
|Journal||Indian Journal of Heterocyclic Chemistry|
|Publication status||Published - 1998|
Udupi, R. H., Kasinath, N., & Bhat, A. R. (1998). Synthesis and biological activity of some 2-(6-methoxynaphthyl) propionamido azetidine-2-ones. Indian Journal of Heterocyclic Chemistry, 7(3), 221-224.