Synthesis and biological activity of some 2-(6-methoxynaphthyl) propionamido azetidine-2-ones

R.H. Udupi, N. Kasinath, A.R. Bhat

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

The hydrazide of 2-(6-methoxy α-naphthyl)-propionic acid (Naproxen) was converted to the Schiff's bases which in turn on reacting with aryl and aryloxy acetyl chlorides yielded the corresponding azetidin-2-ones (4-a-c and 5 a-t). Representative compounds screened for antitubercular activity were proved to be equipotent with streptomycin.
Original languageUndefined/Unknown
Pages (from-to)221-224
Number of pages4
JournalIndian Journal of Heterocyclic Chemistry
Volume7
Issue number3
Publication statusPublished - 1998

Cite this

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title = "Synthesis and biological activity of some 2-(6-methoxynaphthyl) propionamido azetidine-2-ones",
abstract = "The hydrazide of 2-(6-methoxy α-naphthyl)-propionic acid (Naproxen) was converted to the Schiff's bases which in turn on reacting with aryl and aryloxy acetyl chlorides yielded the corresponding azetidin-2-ones (4-a-c and 5 a-t). Representative compounds screened for antitubercular activity were proved to be equipotent with streptomycin.",
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pages = "221--224",
journal = "Indian Journal of Heterocyclic Chemistry",
issn = "0971-1627",
publisher = "National Academy of Chemistry",
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Synthesis and biological activity of some 2-(6-methoxynaphthyl) propionamido azetidine-2-ones. / Udupi, R.H.; Kasinath, N.; Bhat, A.R.

In: Indian Journal of Heterocyclic Chemistry, Vol. 7, No. 3, 1998, p. 221-224.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Synthesis and biological activity of some 2-(6-methoxynaphthyl) propionamido azetidine-2-ones

AU - Udupi, R.H.

AU - Kasinath, N.

AU - Bhat, A.R.

N1 - cited By 16

PY - 1998

Y1 - 1998

N2 - The hydrazide of 2-(6-methoxy α-naphthyl)-propionic acid (Naproxen) was converted to the Schiff's bases which in turn on reacting with aryl and aryloxy acetyl chlorides yielded the corresponding azetidin-2-ones (4-a-c and 5 a-t). Representative compounds screened for antitubercular activity were proved to be equipotent with streptomycin.

AB - The hydrazide of 2-(6-methoxy α-naphthyl)-propionic acid (Naproxen) was converted to the Schiff's bases which in turn on reacting with aryl and aryloxy acetyl chlorides yielded the corresponding azetidin-2-ones (4-a-c and 5 a-t). Representative compounds screened for antitubercular activity were proved to be equipotent with streptomycin.

M3 - Article

VL - 7

SP - 221

EP - 224

JO - Indian Journal of Heterocyclic Chemistry

JF - Indian Journal of Heterocyclic Chemistry

SN - 0971-1627

IS - 3

ER -