Cyclocondensation of benzofuran chalcones (2) with Norfloxacin and Mefenamic acid hydrazides resulted in the formation of benzofuran 2-pyrazolines (3,4). Chalcones (2) were synthesized by Claisen-Schmidt condensation involving treatment of 2-acetyl benzofuran with different aromatic aldehydes. The compounds were evaluated for antitubercular, antimicrobial and antiinflammatory activities.
|Number of pages||4|
|Journal||Indian Journal of Heterocyclic Chemistry|
|Publication status||Published - 2004|
Harinadha Babu, V., Manna, S. K., Surendran, S., Srinivasan, K. K., & Varadaraj Bhat, G. (2004). Synthesis and biological evaluation of 1,3,5-trisubstituted pyrazolines bearing benzofuran. Indian Journal of Heterocyclic Chemistry, 13(3), 253-256.