Synthesis and biological evaluation of 4-(substituted aryl)-1-(N-indolyl acetamidyl)-3-chloro-2-azetidinones

P.V.R. Chowdary, S.G. Jawarkar, K. Shashikala Rani, G. Rao, V. Prasad

Research output: Contribution to journalArticle

Abstract

Various 4-(substituted aryl)-1-(N-indolyl acetamidyl)-3-chloro-2- azetidinones were prepared by condensing N-(arylidine hydrazidomethyl)-indoles with chloroacetyl chloride. Their structures were established by chemical tests, IR and 1HNMR spectral data. These synthesized compounds were tested for their antibacterial, antifungal, antitubercular and antiinflammatory activities.
Original languageEnglish
Pages (from-to)610-614
Number of pages5
JournalIndian Journal of Pharmaceutical Sciences
Volume67
Issue number5
Publication statusPublished - 2005
Externally publishedYes

    Fingerprint

Cite this

Chowdary, P. V. R., Jawarkar, S. G., Shashikala Rani, K., Rao, G., & Prasad, V. (2005). Synthesis and biological evaluation of 4-(substituted aryl)-1-(N-indolyl acetamidyl)-3-chloro-2-azetidinones. Indian Journal of Pharmaceutical Sciences, 67(5), 610-614.