Synthesis and biological evaluation of benzofuran incorporated benzodiazepines

V. Harinadha Babu, A. Gupta, K.K. Srinivasan, K.S.R. Pai

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6 Citations (Scopus)

Abstract

Condensation of 2-acetyl benzofuran (1) with different aromatic aldehydes in alcoholic NaOH afforded different chalcones (2). Cyclocondensation of these chalcones with o-phenylenediamine gave benzofuran benzodiazepines (3). The synthesized compounds were evaluated for antimicrobial, sedative and hypnotic activities.
Original languageEnglish
Pages (from-to)267-268
Number of pages2
JournalIndian Journal of Heterocyclic Chemistry
Volume14
Issue number3
Publication statusPublished - 2005

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