Synthesis and biological evaluation of some novel quinazolones

E. Jessy, A. Sambanthan, A. Joseph, C. Sridevi, K. Srinivasan

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20 Citations (Scopus)

Abstract

In view of the potent antimicrobial and antiinflammatory activities exhibited by quinazolin-4-(3H)-ones, a series of novel 2, 3-disubstituted-3,1- quinazolin-4-(3H) ones have been synthesized. The synthesized compounds were screened for antibacterial and antiinflammatory activities. Compounds 3a and 3l showed significant antiinflammatory activity comparable to ibuprofen, while the compound 3J showed antibacterial activity comparable to ciprofloxacin.
Original languageEnglish
Pages (from-to)476-478
Number of pages3
JournalIndian Journal of Pharmaceutical Sciences
Volume69
Issue number3
Publication statusPublished - 2007

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