Synthesis and characterization of 2-(4-((1-alkyl or aryl-1H-1,2,3-triazol- 4-yl)methoxy)phenyl)naphtho[1,2-d]oxazoles for protein tyrosine phosphatase 1B inhibitory activity

Sridhar Madabhushi, Narsaiah Chinthala, Abhinav Kanwal, Gagandeep Kaur, Sanjay K. Banerjee

Research output: Contribution to journalArticlepeer-review

Abstract

2-(4-((1-Alkyl/aryl-1H-1,2,3-triazol-4-yl)methoxy) phenyl)naphtho[1,2-d] were prepared and evaluated as protein tyrosine phosphatase 1B (PTP1B) inhibitors. In this study, two new compounds with potent PTP1B inhibitory activity were identified.

Original languageEnglish
Pages (from-to)2062-2069
Number of pages8
JournalMedicinal Chemistry Research
Volume23
Issue number4
DOIs
Publication statusPublished - 01-01-2014

All Science Journal Classification (ASJC) codes

  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Organic Chemistry

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