Synthesis and evaluation of some substituted 2-arylamino coumarinyl thiazoles as potential NSAIDs

K. N. Venugopala, B. S. Jayashree, Mahesh Attimarad

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15 Citations (Scopus)

Abstract

Substituted 2′-arylamino-4′-(3-coumarinyl) thiazoles (5a-j) and 2′-arylamino-4′-(6-bromo-3-coumarinyl) thiazoles (5k-v) were synthesized by the condensation of respective 3-bromoacetyl-coumarins with thiourea and substituted phenylthioureas. Finally the compounds were characterized by spectral data and screened for their analgesic and anti-inflammatory activities. Some of these compounds exhibited promising activity.

Original languageEnglish
Pages (from-to)872-876
Number of pages5
JournalAsian Journal of Chemistry
Volume16
Issue number2
Publication statusPublished - 01-04-2004

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All Science Journal Classification (ASJC) codes

  • Chemistry(all)

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