Synthesis, anthelmintic and anti-inflammatory activities of some novel imidazothiazole sulfides and sulfones

Nitinkumar S. Shetty, I. A M Khazi, Chuljin Ahn

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13 Citations (Scopus)

Abstract

A series of new 6-aryl-3-(3,4-dimethoxy-phenyl)-2-phenylsulfanyl-imidazo[2, 1-b]-thiazole (5a-c) and 6-aryl-2-benzenesulfonyl-3-(3,4-dimethoxy-phenyl) imidazo[2,1-b]- thiazole (6a-c) have been prepared and characterized by analytical and spectral methods. The title compounds 5a-c and 6a-c were obtained by the reaction of 4-(3,4-dimethoxy-phenyl)-5-phenylsulfanyl-thiazol-2-ylamine (3) and 5-benzenesulfonyl-4-(3,4-dimethoxy -phenyl)thiazol-2-ylamine (4) with various phenacyl bromides in anhydrous ethanol. These newly synthesized compounds (5a-c and 6a-c) were screened for their anthelmintic and anti-inflammatory activities, where they have displayed better activities.

Original languageEnglish
Pages (from-to)2337-2340
Number of pages4
JournalBulletin of the Korean Chemical Society
Volume31
Issue number8
DOIs
Publication statusPublished - 20-08-2010

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All Science Journal Classification (ASJC) codes

  • Chemistry(all)

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