Synthesis, characterization and antibacterial activity studies on some fluorine containing quinoline-4-carboxylic acids and their derivatives

B. Shivarama Holla, K. Narayana Poojary, Boja Poojary, K. Subrahmanya Bhat, N. Suchetha Kumari

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21 Citations (Scopus)


A series of 3-substituted-1,2,4-triazolo[3,4-6]-1,3,4-thiadiazol-6-yl-2-(2, 4-dichloro-5-fluorophenyl)quinolines 5 have been synthesized by the condensation of hitherto unreported quinoline-4-carboxylic acids 3 with various 3-substituted-4-amino-5-mercapto-1,2,4-triazoles 4. The structures of newly synthesized compounds have been confirmed on the basis of elemental analysis, IR, 1H NMR and mass spectral data. The newly synthesized compounds are evaluated for their antibacterial activities.

Original languageEnglish
Pages (from-to)2114-2119
Number of pages6
JournalIndian Journal of Chemistry - Section B Organic and Medicinal Chemistry
Issue number10
Publication statusPublished - 10-2005


All Science Journal Classification (ASJC) codes

  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Organic Chemistry

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