Synthesis, characterization and determination of partition coefficient of some triazole derivatives of coumarins for their antimicrobial activity

B. S. Jayashree; A. R. Sahu; M. Srinivasa Murthy; K. N. Venugopala

Synthesis, characterization and determination of partition coefficient of some triazole derivatives of coumarins for their antimicrobial activity

B. S. Jayashree, A. R. Sahu, M. Srinivasa Murthy, K. N. Venugopala

Department of Pharmaceutical Chemistry, Manipal College of Pharmaceutical Sciences, Manipal

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

The triazolo-thiadiazinyl coumarins have been synthesized by the action of 3-bromoacetyl coumarin and substituted triazoles. The synthesized compounds have been characterized by IR, ¹H-NMR and mass spectral analysis. An attempt to determine the hydrophobia parameter (partition coefficient) was also established. All the test compounds were screened for their antimicrobial activity by qualitative and quantitative method.

Original language	English
Pages (from-to)	73-78
Number of pages	6
Journal	Asian Journal of Chemistry
Volume	19
Issue number	1
Publication status	Published - 01-01-2007

All Science Journal Classification (ASJC) codes

Chemistry(all)

Cite this

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AU - Venugopala, K. N.

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AB - The triazolo-thiadiazinyl coumarins have been synthesized by the action of 3-bromoacetyl coumarin and substituted triazoles. The synthesized compounds have been characterized by IR, 1H-NMR and mass spectral analysis. An attempt to determine the hydrophobia parameter (partition coefficient) was also established. All the test compounds were screened for their antimicrobial activity by qualitative and quantitative method.

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Synthesis, characterization and determination of partition coefficient of some triazole derivatives of coumarins for their antimicrobial activity

Abstract

All Science Journal Classification (ASJC) codes

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