TY - JOUR
T1 - Synthesis of some new biologically active thiadiazolotriazinones - Part II
AU - Holla, B. Shivarama
AU - Sarojini, B. K.
AU - Shridhara, K.
AU - Antony, Georgy
PY - 1999/3/31
Y1 - 1999/3/31
N2 - 4-Amino-6-phenyl/methyl-3-mercapto-1,2,4-triazin-5(4H)-ones (1) are condensed with an aromatic carboxylic acid, aryloxyacetic acid or anilinoacetic acid (2), to yield 7-substituted-3-phenyl/methyl-4H-1,3,4-thiadiazolo-[2,3-c]-1,2,4-triazin-4-ones (3). Phosphorus oxychloride is used as a cyclizing agent. All the synthesized compounds are screened for their antibacterial activities against S. aureus, E. coli, P. aeruginosa and G. bacillus.
AB - 4-Amino-6-phenyl/methyl-3-mercapto-1,2,4-triazin-5(4H)-ones (1) are condensed with an aromatic carboxylic acid, aryloxyacetic acid or anilinoacetic acid (2), to yield 7-substituted-3-phenyl/methyl-4H-1,3,4-thiadiazolo-[2,3-c]-1,2,4-triazin-4-ones (3). Phosphorus oxychloride is used as a cyclizing agent. All the synthesized compounds are screened for their antibacterial activities against S. aureus, E. coli, P. aeruginosa and G. bacillus.
UR - http://www.scopus.com/inward/record.url?scp=0033620393&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033620393&partnerID=8YFLogxK
U2 - 10.1016/S0014-827X(99)00008-7
DO - 10.1016/S0014-827X(99)00008-7
M3 - Article
C2 - 10371027
AN - SCOPUS:0033620393
VL - 54
SP - 149
EP - 151
JO - ChemMedChem
JF - ChemMedChem
SN - 1860-7179
IS - 3
ER -