Abstract
4-Amino-6-phenyl/methyl-3-mercapto-1,2,4-triazin-5(4H)-ones (1) are condensed with an aromatic carboxylic acid, aryloxyacetic acid or anilinoacetic acid (2), to yield 7-substituted-3-phenyl/methyl-4H-1,3,4-thiadiazolo-[2,3-c]-1,2,4-triazin-4-ones (3). Phosphorus oxychloride is used as a cyclizing agent. All the synthesized compounds are screened for their antibacterial activities against S. aureus, E. coli, P. aeruginosa and G. bacillus.
| Original language | English |
|---|---|
| Pages (from-to) | 149-151 |
| Number of pages | 3 |
| Journal | Farmaco |
| Volume | 54 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 31-03-1999 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Drug Discovery
- Pharmaceutical Science
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Synthesis of some new biologically active thiadiazolotriazinones - Part II. / Holla, B. Shivarama; Sarojini, B. K.; Shridhara, K.; Antony, Georgy.
In: Farmaco, Vol. 54, No. 3, 31.03.1999, p. 149-151.Research output: Contribution to journal › Article
TY - JOUR
T1 - Synthesis of some new biologically active thiadiazolotriazinones - Part II
AU - Holla, B. Shivarama
AU - Sarojini, B. K.
AU - Shridhara, K.
AU - Antony, Georgy
PY - 1999/3/31
Y1 - 1999/3/31
N2 - 4-Amino-6-phenyl/methyl-3-mercapto-1,2,4-triazin-5(4H)-ones (1) are condensed with an aromatic carboxylic acid, aryloxyacetic acid or anilinoacetic acid (2), to yield 7-substituted-3-phenyl/methyl-4H-1,3,4-thiadiazolo-[2,3-c]-1,2,4-triazin-4-ones (3). Phosphorus oxychloride is used as a cyclizing agent. All the synthesized compounds are screened for their antibacterial activities against S. aureus, E. coli, P. aeruginosa and G. bacillus.
AB - 4-Amino-6-phenyl/methyl-3-mercapto-1,2,4-triazin-5(4H)-ones (1) are condensed with an aromatic carboxylic acid, aryloxyacetic acid or anilinoacetic acid (2), to yield 7-substituted-3-phenyl/methyl-4H-1,3,4-thiadiazolo-[2,3-c]-1,2,4-triazin-4-ones (3). Phosphorus oxychloride is used as a cyclizing agent. All the synthesized compounds are screened for their antibacterial activities against S. aureus, E. coli, P. aeruginosa and G. bacillus.
UR - http://www.scopus.com/inward/record.url?scp=0033620393&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033620393&partnerID=8YFLogxK
U2 - 10.1016/S0014-827X(99)00008-7
DO - 10.1016/S0014-827X(99)00008-7
M3 - Article
C2 - 10371027
AN - SCOPUS:0033620393
VL - 54
SP - 149
EP - 151
JO - ChemMedChem
JF - ChemMedChem
SN - 1860-7179
IS - 3
ER -