Synthesis of some new biologically active thiadiazolotriazinones - Part II

B. Shivarama Holla, B. K. Sarojini, K. Shridhara, Georgy Antony

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

4-Amino-6-phenyl/methyl-3-mercapto-1,2,4-triazin-5(4H)-ones (1) are condensed with an aromatic carboxylic acid, aryloxyacetic acid or anilinoacetic acid (2), to yield 7-substituted-3-phenyl/methyl-4H-1,3,4-thiadiazolo-[2,3-c]-1,2,4-triazin-4-ones (3). Phosphorus oxychloride is used as a cyclizing agent. All the synthesized compounds are screened for their antibacterial activities against S. aureus, E. coli, P. aeruginosa and G. bacillus.

Original languageEnglish
Pages (from-to)149-151
Number of pages3
JournalFarmaco
Volume54
Issue number3
DOIs
Publication statusPublished - 31-03-1999
Externally publishedYes

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Acids
Bacilli
Carboxylic Acids
Carboxylic acids
Escherichia coli
Bacillus
phosphoryl chloride
metamitron

All Science Journal Classification (ASJC) codes

  • Drug Discovery
  • Pharmaceutical Science

Cite this

Holla, B. S., Sarojini, B. K., Shridhara, K., & Antony, G. (1999). Synthesis of some new biologically active thiadiazolotriazinones - Part II. Farmaco, 54(3), 149-151. https://doi.org/10.1016/S0014-827X(99)00008-7
Holla, B. Shivarama ; Sarojini, B. K. ; Shridhara, K. ; Antony, Georgy. / Synthesis of some new biologically active thiadiazolotriazinones - Part II. In: Farmaco. 1999 ; Vol. 54, No. 3. pp. 149-151.
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Holla, BS, Sarojini, BK, Shridhara, K & Antony, G 1999, 'Synthesis of some new biologically active thiadiazolotriazinones - Part II', Farmaco, vol. 54, no. 3, pp. 149-151. https://doi.org/10.1016/S0014-827X(99)00008-7

Synthesis of some new biologically active thiadiazolotriazinones - Part II. / Holla, B. Shivarama; Sarojini, B. K.; Shridhara, K.; Antony, Georgy.

In: Farmaco, Vol. 54, No. 3, 31.03.1999, p. 149-151.

Research output: Contribution to journalArticle

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AU - Holla, B. Shivarama

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