|Number of pages||8|
|Journal||International Journal of Pharmacy and Pharmaceutical Sciences|
|Publication status||Published - 2010|
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Research output: Contribution to journal › Article
TY - JOUR
T1 - Taste masking technologies: A review
AU - Sharma, S.
AU - Lewis, S.
N1 - Cited By :39 Export Date: 10 November 2017 Correspondence Address: Lewis, S.; Dept of Pharmaceutics, Manipal college of Pharmaceutical Sciences, Manipal University, Manipal 576 104, Karnataka, India; email: email@example.com Chemicals/CAS: acetylsalicylic acid, 493-53-8, 50-78-2, 53663-74-4, 53664-49-6, 63781-77-1; ampicillin, 69-52-3, 69-53-4, 7177-48-2, 74083-13-9, 94586-58-0; cellulose acetate, 9004-35-7; chloroquine, 132-73-0, 3545-67-3, 50-63-5, 54-05-7; chlorpheniramine maleate, 113-92-8; ciprofloxacin, 85721-33-1; clarithromycin, 81103-11-9; dextromethorphan, 125-69-9, 125-71-3; ephedrine, 299-42-3, 50-98-6; erythromycin, 114-07-8, 70536-18-4; eucalyptus oil, 8000-48-4; eudragit, 24938-16-7, 51822-44-7, 9065-11-6; glycerol stearate, 11099-07-3, 31566-31-1, 8049-07-8; hydroxypropylmethylcellulose, 9004-65-3; ibuprofen, 15687-27-1; levofloxacin, 100986-85-4, 138199-71-0; metronidazole, 39322-38-8, 443-48-1; nizatidine, 76963-41-2; orbifloxacin, 113617-63-3; paracetamol, 103-90-2; paroxetine, 61869-08-7; ranitidine, 66357-35-5, 66357-59-3; roxithromycin, 80214-83-1; sildenafil, 139755-83-2; theophylline, 58-55-9, 5967-84-0, 8055-07-0, 8061-56-1, 99007-19-9; thymol, 89-83-8; triclosan, 3380-34-5; zinc acetate, 557-34-6 References: www.foodiesite.com/articles/2000-11/cheese.jsp; www.umds.ac.vk/physiology/jimtasteolf.htm; www.cf.ac.vk.biosi/staft/jacob/teaching/sensoy/taste.htm; Gyton, C., The chemical senses-Taste and smell (1986) Textbook of Medical Physiology, p. 745. , 7th ed. 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No. 5,635,200 to Glaxo Group ltd; (1980) Ion Exchange Resin In Microencapsulation, p. 150. , Deasy, Newyork: Marcel Dekker Inc; Reynold, E.V., Ion exchange resin (1982) Martindale the Extra Pharmacopoeia, p. 869. , 28th Edition. London: Pharmaceutical Press; Swarbrick, J., Boylon, S.C., (1990) Ion Exchange Resin. In Encylopedia of Pharmaceutical Technology, 8, pp. 203-216. , New York: Marcel Dekker Inc; Cristal, M., Particle Application of ion exchange resins (1985) Manuf. Chem, 56, pp. 50-53; Denney, R.C., Jeffery, G.H., Ion exchange (1978) Vogel's Textbook of Quantitative Inorganic Analysis, pp. 165-172. , 4th edition. England: Longman scientific and Technical; Eichman, M.L., (1999) Drug Resin Complexes Stabilized By Chelating Agents, , U.S. Pat. No. 5,980,882 to Medeva Pharm. Manuf; Motyoka, S., Nairn, J.G., Influence of coating on release rate of anion from ion exchange resins beads (1978) J. Pharm. 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PY - 2010
Y1 - 2010
N2 - Oral administration of pharmaceuticals is one of the most popular method of drug dilevery. Many orally administered drugs elicit bitter taste. Palatability is an extremly important factor in ensuring the likelihood that the recepient will intake the pharmaceuticals. A constant problem is in treatment of patient is their inability or unwillingness to swallow solid dosage form such as tablets specially in children and the elderly. These dosage form permit perceptible exposure of active drug ingredient to the taste bud. Accordingly, masking of unpleasent taste characterstics of drug is an important factor in formulation of these agents."The worse the taste of the medication, the better the cure" was once the prevailing attitude. Today a change in patient attitude and development of taste masking technique has reversed this opinion. Patients now expect and demand formulations that are pleasently, or atleast tolerably, flavored.1 This article reviews the earlier methodologies and approaches of taste masking of bitterness reduction.
AB - Oral administration of pharmaceuticals is one of the most popular method of drug dilevery. Many orally administered drugs elicit bitter taste. Palatability is an extremly important factor in ensuring the likelihood that the recepient will intake the pharmaceuticals. A constant problem is in treatment of patient is their inability or unwillingness to swallow solid dosage form such as tablets specially in children and the elderly. These dosage form permit perceptible exposure of active drug ingredient to the taste bud. Accordingly, masking of unpleasent taste characterstics of drug is an important factor in formulation of these agents."The worse the taste of the medication, the better the cure" was once the prevailing attitude. Today a change in patient attitude and development of taste masking technique has reversed this opinion. Patients now expect and demand formulations that are pleasently, or atleast tolerably, flavored.1 This article reviews the earlier methodologies and approaches of taste masking of bitterness reduction.
M3 - Article
VL - 2
SP - 6
EP - 13
JO - International Journal of Pharmacy and Pharmaceutical Sciences
JF - International Journal of Pharmacy and Pharmaceutical Sciences
SN - 0975-1491
IS - 2