The clinical management of hyperemesis gravidarum

Shipra Sonkusare

Research output: Contribution to journalReview article

18 Citations (Scopus)

Abstract

Hyperemesis gravidarum is a severe and disabling condition with potentially life-threatening complications. It is likely to have a multifactorial etiology which contributes to the difficulty in treatment. Treatment is supportive with correction of dehydration and electrolyte disturbance, antiemetic therapy, prevention and treatment of complications like Wernicke's encephalopathy, osmotic demyelination syndrome, thromboembolism, and good psychological support. There are abundant data on the safety of antihistamines, phenothiazines, and metoclopromide in early pregnancy and treatment should therefore not be withheld on the basis of teratogenicity concerns. Thiamine replacement is indicated in hyperemesis gravidarum to prevent development of Wernicke's encephalopathy.

Original languageEnglish
Pages (from-to)1183-1192
Number of pages10
JournalArchives of Gynecology and Obstetrics
Volume283
Issue number6
DOIs
Publication statusPublished - 01-06-2011
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynaecology

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