Aims To determine the dimensions of the human corpus callosum and its parts. The objective was also to know its location in the cerebral hemisphere of South Indians. Methods Twenty mid-sagittal sections from formalin fixed human cadaveric brain specimens were used for this study and the parameters recorded were: distances from frontal pole to occipital pole (AB), inferior surface to the superior surface of the brain (CD), frontal pole of brain to genu (AG), occipital pole of cerebrum to corpus callosum splenium (BS), from splenium of corpus callosum to superior colliculus (Ls-SC) and inferior colliculus (Ls-IC), genu to fornix (GF), outer curvature O (G-S) and inner curvature I (G-S) from genu to splenium, the entire outer curvature (OUTCR) and inner curvature (INCUR) from beginning of corpus callosum rostrum to the splenium end. We did also measure the thicknesses of its splenium (S), isthmus (I), body (T), genu (G) and rostrum (R). Results Statistical analysis using correlation study showed significance between A-B and B-S, O (G-S) and INCUR, O (G-S) and OUTCR, A-G and R, T and I. Highly significant correlations were found between C-D and Ls-IC, O (G-S) and I (G-S), I (G-S) and G-F, G-F, and G. Very highly significant correlations were seen between I (G-S) and INCUR, Ls-SC, and Ls-IC, T and S. Conclusion This morphometric study on the corpus callosum provides data that could be valuable in the diagnosis of lesions of the corpus callosum. The data are of particular relevance to neurologists and radiologists.
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