La sindrome epato-renale: una revisione della letteratura

Translated title of the contribution: The hepatorenal syndrome - a review

Mayoor V. Prabhu, B. Sukanya, B. H. Santosh Pai, Sreedhar Reddy

Research output: Contribution to journalReview article

3 Citations (Scopus)

Abstract

The Hepato Renal Syndrome (HRS) remains a diagnostic and therapeutic conundrum. Controversies persist in the definition, understanding of pathophysiological mechanisms, diagnosis, and therapy of renal dysfunction complicating End Stage Liver Disease (ESLD).While ESLD is complicated by dysfunction in multiple organs, renal disease holds particular bearing on long term outcomes. Liver transplantation is the therapy of choice for ESLD-and co existing renal dysfunction makes it more difficult and challenging. Given that a bare minimum of patients with ESLD will ultimately receive a liver transplant, especially in the developing world, renal dysfunction may ultimately portend untimely death in a many of these patients. It is also critical to recognize the fact that HRS is not the sole cause of renal failure in ESLD. Hence, early recognition and therapy may prolong life even in those who will not receive a transplant for multitude of reasons. Renal Replacement Therapy (RRT) is also a challenge in this patient population, leading to issues with hemodynamics, vascular access and anticoagulation. We take a look at recent literature and advances in the understanding of the pathophysiology of this particularly difficult condition, and its diagnosis and management.

Original languageItalian
JournalGiornale italiano di nefrologia : organo ufficiale della Società italiana di nefrologia
Volume31
Issue number3
Publication statusPublished - 01-05-2014

Fingerprint

Hepatorenal Syndrome
End Stage Liver Disease
Kidney
Transplants
Renal Replacement Therapy
Secondary Prevention
Liver Transplantation
Renal Insufficiency
Blood Vessels
Therapeutics
Hemodynamics
Liver
Population

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

@article{203c8e28b1514f149a1b16c2820278cd,
title = "La sindrome epato-renale: una revisione della letteratura",
abstract = "The Hepato Renal Syndrome (HRS) remains a diagnostic and therapeutic conundrum. Controversies persist in the definition, understanding of pathophysiological mechanisms, diagnosis, and therapy of renal dysfunction complicating End Stage Liver Disease (ESLD).While ESLD is complicated by dysfunction in multiple organs, renal disease holds particular bearing on long term outcomes. Liver transplantation is the therapy of choice for ESLD-and co existing renal dysfunction makes it more difficult and challenging. Given that a bare minimum of patients with ESLD will ultimately receive a liver transplant, especially in the developing world, renal dysfunction may ultimately portend untimely death in a many of these patients. It is also critical to recognize the fact that HRS is not the sole cause of renal failure in ESLD. Hence, early recognition and therapy may prolong life even in those who will not receive a transplant for multitude of reasons. Renal Replacement Therapy (RRT) is also a challenge in this patient population, leading to issues with hemodynamics, vascular access and anticoagulation. We take a look at recent literature and advances in the understanding of the pathophysiology of this particularly difficult condition, and its diagnosis and management.",
author = "Prabhu, {Mayoor V.} and B. Sukanya and {Santosh Pai}, {B. H.} and Sreedhar Reddy",
year = "2014",
month = "5",
day = "1",
language = "Italian",
volume = "31",
journal = "Giornale italiano di nefrologia : organo ufficiale della Società italiana di nefrologia",
issn = "0393-5590",
publisher = "Wichtig Publishing",
number = "3",

}

La sindrome epato-renale : una revisione della letteratura. / Prabhu, Mayoor V.; Sukanya, B.; Santosh Pai, B. H.; Reddy, Sreedhar.

In: Giornale italiano di nefrologia : organo ufficiale della Società italiana di nefrologia, Vol. 31, No. 3, 01.05.2014.

Research output: Contribution to journalReview article

TY - JOUR

T1 - La sindrome epato-renale

T2 - una revisione della letteratura

AU - Prabhu, Mayoor V.

AU - Sukanya, B.

AU - Santosh Pai, B. H.

AU - Reddy, Sreedhar

PY - 2014/5/1

Y1 - 2014/5/1

N2 - The Hepato Renal Syndrome (HRS) remains a diagnostic and therapeutic conundrum. Controversies persist in the definition, understanding of pathophysiological mechanisms, diagnosis, and therapy of renal dysfunction complicating End Stage Liver Disease (ESLD).While ESLD is complicated by dysfunction in multiple organs, renal disease holds particular bearing on long term outcomes. Liver transplantation is the therapy of choice for ESLD-and co existing renal dysfunction makes it more difficult and challenging. Given that a bare minimum of patients with ESLD will ultimately receive a liver transplant, especially in the developing world, renal dysfunction may ultimately portend untimely death in a many of these patients. It is also critical to recognize the fact that HRS is not the sole cause of renal failure in ESLD. Hence, early recognition and therapy may prolong life even in those who will not receive a transplant for multitude of reasons. Renal Replacement Therapy (RRT) is also a challenge in this patient population, leading to issues with hemodynamics, vascular access and anticoagulation. We take a look at recent literature and advances in the understanding of the pathophysiology of this particularly difficult condition, and its diagnosis and management.

AB - The Hepato Renal Syndrome (HRS) remains a diagnostic and therapeutic conundrum. Controversies persist in the definition, understanding of pathophysiological mechanisms, diagnosis, and therapy of renal dysfunction complicating End Stage Liver Disease (ESLD).While ESLD is complicated by dysfunction in multiple organs, renal disease holds particular bearing on long term outcomes. Liver transplantation is the therapy of choice for ESLD-and co existing renal dysfunction makes it more difficult and challenging. Given that a bare minimum of patients with ESLD will ultimately receive a liver transplant, especially in the developing world, renal dysfunction may ultimately portend untimely death in a many of these patients. It is also critical to recognize the fact that HRS is not the sole cause of renal failure in ESLD. Hence, early recognition and therapy may prolong life even in those who will not receive a transplant for multitude of reasons. Renal Replacement Therapy (RRT) is also a challenge in this patient population, leading to issues with hemodynamics, vascular access and anticoagulation. We take a look at recent literature and advances in the understanding of the pathophysiology of this particularly difficult condition, and its diagnosis and management.

UR - http://www.scopus.com/inward/record.url?scp=84995977153&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84995977153&partnerID=8YFLogxK

M3 - Review article

C2 - 25030015

AN - SCOPUS:84995977153

VL - 31

JO - Giornale italiano di nefrologia : organo ufficiale della Società italiana di nefrologia

JF - Giornale italiano di nefrologia : organo ufficiale della Società italiana di nefrologia

SN - 0393-5590

IS - 3

ER -