The review on genetics, epigenetics, risk factors and diagnosis of colon cancer

Maheshwari Rajalekshmi, Chandrashekhara Shastri Shreedhara, Richard Lobo, Polu Picheshwara Rao

Research output: Contribution to journalReview article

Abstract

Colon cancer is the second leading cause of cancer-related death in men and third leading cause in women. The possibility of developing colorectal cancer in women is 4.4% and in men is 4.7%. According to ACS report, 95 thousand new colon cancer cases and 39 thousand new rectal cancer cases were reported in 2017. Among adult 50 years of age and older, the incidence rate has been reduced by 4.5%, and among those younger than age 50, it is increased by 1.8% from 2008-2012. The improvement in early detection and treatment has declined the mortality rates by 2.8% per year from 2003 to 2012. There is no typical signs and symptoms at the early stages of colorectal cancer. Rectal bleeding, cramping pain in lower abdomen, decreased appetite, and weight loss is the symptoms of colorectal cancer. The survival rate of colorectal cancer is 60-64%.

Original languageEnglish
Pages (from-to)5147-5151
Number of pages5
JournalResearch Journal of Pharmacy and Technology
Volume11
Issue number11
DOIs
Publication statusPublished - 01-11-2018

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Epigenomics
Colonic Neoplasms
Colorectal Neoplasms
Appetite
Rectal Neoplasms
Abdomen
Signs and Symptoms
Weight Loss
Survival Rate
Hemorrhage
Pain
Mortality
Incidence
Neoplasms
Therapeutics

All Science Journal Classification (ASJC) codes

  • Pharmacology, Toxicology and Pharmaceutics (miscellaneous)
  • Pharmacology (medical)

Cite this

Rajalekshmi, Maheshwari ; Shreedhara, Chandrashekhara Shastri ; Lobo, Richard ; Rao, Polu Picheshwara. / The review on genetics, epigenetics, risk factors and diagnosis of colon cancer. In: Research Journal of Pharmacy and Technology. 2018 ; Vol. 11, No. 11. pp. 5147-5151.
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abstract = "Colon cancer is the second leading cause of cancer-related death in men and third leading cause in women. The possibility of developing colorectal cancer in women is 4.4{\%} and in men is 4.7{\%}. According to ACS report, 95 thousand new colon cancer cases and 39 thousand new rectal cancer cases were reported in 2017. Among adult 50 years of age and older, the incidence rate has been reduced by 4.5{\%}, and among those younger than age 50, it is increased by 1.8{\%} from 2008-2012. The improvement in early detection and treatment has declined the mortality rates by 2.8{\%} per year from 2003 to 2012. There is no typical signs and symptoms at the early stages of colorectal cancer. Rectal bleeding, cramping pain in lower abdomen, decreased appetite, and weight loss is the symptoms of colorectal cancer. The survival rate of colorectal cancer is 60-64{\%}.",
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The review on genetics, epigenetics, risk factors and diagnosis of colon cancer. / Rajalekshmi, Maheshwari; Shreedhara, Chandrashekhara Shastri; Lobo, Richard; Rao, Polu Picheshwara.

In: Research Journal of Pharmacy and Technology, Vol. 11, No. 11, 01.11.2018, p. 5147-5151.

Research output: Contribution to journalReview article

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AU - Shreedhara, Chandrashekhara Shastri

AU - Lobo, Richard

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