The role of ageing and diabetic complications on autonomic modulation in geriatric population

K. Kishan, R. S. Bindiya, C. Ramaswamy, Sheila R. Pai, Prashanth N. Dixit, K. M. Damodara Gowda, Y. P. Ragavendra Babu, H. N. Harsha Kumar

Research output: Contribution to journalArticlepeer-review


The geriatric population belongs to the age group 70 years and encounter debilitating changes in almost all the system of the body. This study was aimed to record and asses the Heart Rate Variability (HRV) in elderly population involved, to predict and prevent further deterioration by assessing the cardiac function with respect to the cardiac regulatory mechanisms.To assess the autonomic changes, in this study different parameters of HRV were recorded in the people of age above 70yrs and compared with normal individuals belongs to the age less than 70years during normal(N),deep breathing(DB) and cold pressor test(CPT) conditions. Showed that the SDANN, Time domain HRV was decreased as age advances in all the conditions except the CPT condition. This study showed that as age advances the autonomic activity decreases, the degree of decrease is more in sympathetic part than parasympathetic.

Original languageEnglish
Pages (from-to)7-12
Number of pages6
JournalResearch Journal of Pharmaceutical, Biological and Chemical Sciences
Issue number2
Publication statusPublished - 01-04-2011

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)


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