The study of pulmonary tuberculosis in diabetes mellitus patients

S. Hariprasad, M. R. Ramakrishna, R. R. Trupti, Sreekantha, S. S. Avinash, Vinodchandran

Research output: Contribution to journalArticle

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Abstract

OBJECTIVES: Clinical and radiological study of pulmonary tuberculosis in diabetic patients. METHODS: 100 cases of diabetes mellitus with pulmonary tuberculosis were studied. Their clinical profile and chest radiograph results were analyzed. RESULTS: The predominant clinical symptoms noted were anorexia (80%), cough (73%), fever (56%). 62.5% of male patients were smokers.Clubbing was noted in 10% of our patients. Average duration of diabetes was 6.6 years. 51% of patients were anemic and 52% of patients had an erythrocyte sedimentation rate above 50mm/hr. The average FBS value was 234.4 mg/dl. 81% of patients were sputum positive for acid fast bacilli under the age of 40 years. Cavitary lesions were noted in about 53% of patients. 38% of patients had infiltration. Fibrosis was noted in 37% of patients above 40 years. Lower lung field involvement was noted in 32% of patients and was more common in patients greater than 40 years. INTERPRETATION AND CONCLUSION: Multiple cavities and multiple lobe involvement are more common in tuberculous diabetics and lower lung field is involved more commonly in older age group patients.Severe hyperglycemia appears to be a contributory factor to the development of pulmonary tuberculosis in diabetics.Diabetes appears to have no effect on the presenting features of pulmonary tuberculosis to a large extent.

Original languageEnglish
JournalInternational Journal of Pharma and Bio Sciences
Volume4
Issue number2
Publication statusPublished - 01-06-2013
Externally publishedYes

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Medical problems
Pulmonary Tuberculosis
Diabetes Mellitus
Bacilli
Sedimentation
Infiltration
Acids
Lung
Blood Sedimentation
Anorexia
Sputum
Cough
Hyperglycemia
Bacillus
Fibrosis
Fever
Thorax
Age Groups

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Biochemistry
  • Molecular Biology
  • Cell Biology

Cite this

Hariprasad, S., Ramakrishna, M. R., Trupti, R. R., Sreekantha, Avinash, S. S., & Vinodchandran (2013). The study of pulmonary tuberculosis in diabetes mellitus patients. International Journal of Pharma and Bio Sciences, 4(2).
Hariprasad, S. ; Ramakrishna, M. R. ; Trupti, R. R. ; Sreekantha ; Avinash, S. S. ; Vinodchandran. / The study of pulmonary tuberculosis in diabetes mellitus patients. In: International Journal of Pharma and Bio Sciences. 2013 ; Vol. 4, No. 2.
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Hariprasad, S, Ramakrishna, MR, Trupti, RR, Sreekantha, Avinash, SS & Vinodchandran 2013, 'The study of pulmonary tuberculosis in diabetes mellitus patients', International Journal of Pharma and Bio Sciences, vol. 4, no. 2.

The study of pulmonary tuberculosis in diabetes mellitus patients. / Hariprasad, S.; Ramakrishna, M. R.; Trupti, R. R.; Sreekantha; Avinash, S. S.; Vinodchandran.

In: International Journal of Pharma and Bio Sciences, Vol. 4, No. 2, 01.06.2013.

Research output: Contribution to journalArticle

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N2 - OBJECTIVES: Clinical and radiological study of pulmonary tuberculosis in diabetic patients. METHODS: 100 cases of diabetes mellitus with pulmonary tuberculosis were studied. Their clinical profile and chest radiograph results were analyzed. RESULTS: The predominant clinical symptoms noted were anorexia (80%), cough (73%), fever (56%). 62.5% of male patients were smokers.Clubbing was noted in 10% of our patients. Average duration of diabetes was 6.6 years. 51% of patients were anemic and 52% of patients had an erythrocyte sedimentation rate above 50mm/hr. The average FBS value was 234.4 mg/dl. 81% of patients were sputum positive for acid fast bacilli under the age of 40 years. Cavitary lesions were noted in about 53% of patients. 38% of patients had infiltration. Fibrosis was noted in 37% of patients above 40 years. Lower lung field involvement was noted in 32% of patients and was more common in patients greater than 40 years. INTERPRETATION AND CONCLUSION: Multiple cavities and multiple lobe involvement are more common in tuberculous diabetics and lower lung field is involved more commonly in older age group patients.Severe hyperglycemia appears to be a contributory factor to the development of pulmonary tuberculosis in diabetics.Diabetes appears to have no effect on the presenting features of pulmonary tuberculosis to a large extent.

AB - OBJECTIVES: Clinical and radiological study of pulmonary tuberculosis in diabetic patients. METHODS: 100 cases of diabetes mellitus with pulmonary tuberculosis were studied. Their clinical profile and chest radiograph results were analyzed. RESULTS: The predominant clinical symptoms noted were anorexia (80%), cough (73%), fever (56%). 62.5% of male patients were smokers.Clubbing was noted in 10% of our patients. Average duration of diabetes was 6.6 years. 51% of patients were anemic and 52% of patients had an erythrocyte sedimentation rate above 50mm/hr. The average FBS value was 234.4 mg/dl. 81% of patients were sputum positive for acid fast bacilli under the age of 40 years. Cavitary lesions were noted in about 53% of patients. 38% of patients had infiltration. Fibrosis was noted in 37% of patients above 40 years. Lower lung field involvement was noted in 32% of patients and was more common in patients greater than 40 years. INTERPRETATION AND CONCLUSION: Multiple cavities and multiple lobe involvement are more common in tuberculous diabetics and lower lung field is involved more commonly in older age group patients.Severe hyperglycemia appears to be a contributory factor to the development of pulmonary tuberculosis in diabetics.Diabetes appears to have no effect on the presenting features of pulmonary tuberculosis to a large extent.

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Hariprasad S, Ramakrishna MR, Trupti RR, Sreekantha, Avinash SS, Vinodchandran. The study of pulmonary tuberculosis in diabetes mellitus patients. International Journal of Pharma and Bio Sciences. 2013 Jun 1;4(2).