The therapeutic potential of the labdane diterpenoid forskolin

Bahare Salehi, Mariola Staniak, Katarzyna Czopek, Anna Stepień, Kamal Dua, Ridhima Wadhwa, Dinesh Kumar Chellappan, Oksana Sytar, Marian Brestic, Namrata Ganesh Bhat, Nanjangud Venkatesh Anil Kumar, María del Mar Contreras, Farukh Sharopov, William C. Cho, Javad Sharifi-Rad

Research output: Contribution to journalReview articlepeer-review

2 Citations (Scopus)

Abstract

Forskolin is mainly found in the root of a plant called Coleus forskohlii (Willd.) Briq., which has been used in the traditional medicine of Indian Ayurvedic and Southeast Asia since ancient times. Forskolin is responsible for the pharmacological activity of this species. Forskolin is a labdane diterpenoid with a wide biological effect. Several studies suggested a positive role of forskolin on heart complications, respiratory disorders, high blood pressure, obesity, and asthma. There are numerous clinical and pre-clinical studies representing the effect of forskolin on the above-mentioned disorders but more clinical studies need to be performed to support its efficacy.

Original languageEnglish
Article number4089
JournalApplied Sciences (Switzerland)
Volume9
Issue number19
DOIs
Publication statusPublished - 01-10-2019

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Instrumentation
  • Engineering(all)
  • Process Chemistry and Technology
  • Computer Science Applications
  • Fluid Flow and Transfer Processes

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