The therapeutic potential of the labdane diterpenoid forskolin

Bahare Salehi, Mariola Staniak, Katarzyna Czopek, Anna Stepień, Kamal Dua, Ridhima Wadhwa, Dinesh Kumar Chellappan, Oksana Sytar, Marian Brestic, Namrata Ganesh Bhat, Nanjangud Venkatesh Anil Kumar, María del Mar Contreras, Farukh Sharopov, William C. Cho, Javad Sharifi-Rad

Research output: Contribution to journalReview article

Abstract

Forskolin is mainly found in the root of a plant called Coleus forskohlii (Willd.) Briq., which has been used in the traditional medicine of Indian Ayurvedic and Southeast Asia since ancient times. Forskolin is responsible for the pharmacological activity of this species. Forskolin is a labdane diterpenoid with a wide biological effect. Several studies suggested a positive role of forskolin on heart complications, respiratory disorders, high blood pressure, obesity, and asthma. There are numerous clinical and pre-clinical studies representing the effect of forskolin on the above-mentioned disorders but more clinical studies need to be performed to support its efficacy.

Original languageEnglish
Article number4089
JournalApplied Sciences (Switzerland)
Volume9
Issue number19
DOIs
Publication statusPublished - 01-10-2019

Fingerprint

Diterpenes
Blood pressure
Colforsin
Medicine
asthma
obesity
disorders
Southeast Asia
blood pressure
biological effects
activity (biology)
medicine
labdane

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Instrumentation
  • Engineering(all)
  • Process Chemistry and Technology
  • Computer Science Applications
  • Fluid Flow and Transfer Processes

Cite this

Salehi, B., Staniak, M., Czopek, K., Stepień, A., Dua, K., Wadhwa, R., ... Sharifi-Rad, J. (2019). The therapeutic potential of the labdane diterpenoid forskolin. Applied Sciences (Switzerland), 9(19), [4089]. https://doi.org/10.3390/app9194089
Salehi, Bahare ; Staniak, Mariola ; Czopek, Katarzyna ; Stepień, Anna ; Dua, Kamal ; Wadhwa, Ridhima ; Chellappan, Dinesh Kumar ; Sytar, Oksana ; Brestic, Marian ; Bhat, Namrata Ganesh ; Kumar, Nanjangud Venkatesh Anil ; Contreras, María del Mar ; Sharopov, Farukh ; Cho, William C. ; Sharifi-Rad, Javad. / The therapeutic potential of the labdane diterpenoid forskolin. In: Applied Sciences (Switzerland). 2019 ; Vol. 9, No. 19.
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Salehi, B, Staniak, M, Czopek, K, Stepień, A, Dua, K, Wadhwa, R, Chellappan, DK, Sytar, O, Brestic, M, Bhat, NG, Kumar, NVA, Contreras, MDM, Sharopov, F, Cho, WC & Sharifi-Rad, J 2019, 'The therapeutic potential of the labdane diterpenoid forskolin', Applied Sciences (Switzerland), vol. 9, no. 19, 4089. https://doi.org/10.3390/app9194089

The therapeutic potential of the labdane diterpenoid forskolin. / Salehi, Bahare; Staniak, Mariola; Czopek, Katarzyna; Stepień, Anna; Dua, Kamal; Wadhwa, Ridhima; Chellappan, Dinesh Kumar; Sytar, Oksana; Brestic, Marian; Bhat, Namrata Ganesh; Kumar, Nanjangud Venkatesh Anil; Contreras, María del Mar; Sharopov, Farukh; Cho, William C.; Sharifi-Rad, Javad.

In: Applied Sciences (Switzerland), Vol. 9, No. 19, 4089, 01.10.2019.

Research output: Contribution to journalReview article

TY - JOUR

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AU - Salehi, Bahare

AU - Staniak, Mariola

AU - Czopek, Katarzyna

AU - Stepień, Anna

AU - Dua, Kamal

AU - Wadhwa, Ridhima

AU - Chellappan, Dinesh Kumar

AU - Sytar, Oksana

AU - Brestic, Marian

AU - Bhat, Namrata Ganesh

AU - Kumar, Nanjangud Venkatesh Anil

AU - Contreras, María del Mar

AU - Sharopov, Farukh

AU - Cho, William C.

AU - Sharifi-Rad, Javad

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Salehi B, Staniak M, Czopek K, Stepień A, Dua K, Wadhwa R et al. The therapeutic potential of the labdane diterpenoid forskolin. Applied Sciences (Switzerland). 2019 Oct 1;9(19). 4089. https://doi.org/10.3390/app9194089